_____________________________________________________________

Hydrology Breakthrough vs. USPTO Conspiracy

"Violation of science: bad apples and/or systems failure?"

“Why Bad Apples Spoil the Barrel?”

The Conspiracy – USPTO is running a broad Reinvention Scheme that let Lawyers writing scientific patents and allowing IP rights of issues they are not known in the art!

‘... If you have a point to make about my treatment of hydrological concepts, I ask that you take the time to explain your specific points of disagreement. I note that my work is better represented in my publications (available at http://www.stroockgroup.org/home/publications) than in patents, as the lawyers have been translated the latter into legalese that I do not understand.’

Cornell – I do NOT understand my PATENTS XXX

Food for thought – If an inventor PhD from Harvard can have USPTO issued patents to protect his intellectual property rights but he does NOT understand it, how much the Patent Attorney and Patent Examiner knows about the issue granted protection by US Government. If it holds true, it means that Lawyers know about science more than scientists do. Amazing! I just imagine Albert Einstein trying to get patents with his scientific papers .. . It means that those guys in the patenting affairs would handle Theory of Relativity more than him . . . Now I understand why Americans are the leaders of the world . . . awesome, this is simply magical. Mayday Mr. Snowden . . .mayday mother nature!

My ‘scientific breakthrough’ deals deeply with Hydrogeology/Soil Physics/Hydrology. When I took classes at the Pennsylvania State University of such disciplines during my PhD in Soil Science I remember seeing no single Law student as classmate.

If my patent was being violated I had simple questions to pursue:

· Was it a casual violation or a clear biased trend?

· Had the examiner already cited my patent earlier?

· Did the inventors and examiner have technical-scientific background in the issue?

· Was the violator a wealthy party?

· Was the examiner citing my patent to be sure he was granting new claims not claimed before?

· Why my issued patent was being randomly cited for irrelevant patents and ignored when violated blatantly?

-------------------

This is the tip of the iceberg as of what lies bellow, clearly points out distorted conceptions and beliefs on human culture WHEN LAWS OF MAN IGNORE LAWS OF NATURE.

From: Moulis, Thomas <Thomas.Moulis@uspto.gov>
Date: Fri, Aug 7, 2015 at 12:40 PM
Subject: RE: Conspiracy and Brainwashing III – USPTO is preaching to their Patent Examiners that they do not need to be known in the art for judging and allowing IP rights when issuing patents!
To: Elson Silva, PhD <tubarc@gmail.com>

You are a fool---

If you can’t understand legal or technical writing, you have no business blogging about it

“Wicking” is a term of art---fluid will travel in any direction via the fibers—regardless of gravity

-------------------

"Wick/wicking is in the patent classification system but not on HYDROLOGY textbooks."

LEGAL WICKING as the term of the art regardless of gravity confirms USPTO long standing bias ignoring hydrology on conductivity parameters of issued patents (11/30/23):

Thermal/Heat Conductivity        176.074 pat.
Electric/Electrical Conductivity      139.254 pat.
Hydraulic Conductivity           1.329 pat.
Unsaturated Hydraulic Conductivity      38 pat.
Wick/wicking        66.415 pat.

The US Government states that LEGAL WICKING is not technical, being inert to gravity LAW, meaning that LEGAL OIL LAMPS and LEGAL CANDLES can work upsided down. This sort of deceiving is behind the Economic Melting Down of 2008 burning about 41 trillion dollars, also dumping 1,1 million American as the leader of the COVID-19 pandemic catastrophe that  took around 7 million lives world widely. In addition, obesity and sedentarism letting human beings miss brain capacity by becoming grumpier and dumber on neurogenesis effect.
Science is our understanding on nature functioning. Humans learn to respect nature early as babies on the first steps taming gravity for walking and running. Soon we understand the consequences of missteping and falling down. Therefore, all issued patents dealing with wick/wicking are CERTAINLY frauded because PATENT EXAMINERS ignored their homework from the beginning of their lives - GRAVITY.

Sir Isaac Newton defined the Law of Universal Gravitation in 1687. He was inspired to formulate his theory of gravitation by watching the fall of an apple from a tree.

---------------------------------

De: Owen, Steven [mailto:steven.owen@uconn.edu]
Enviada em: quarta-feira, 5 de outubro de 2011 11:36
Para: Elson Silva, PhD
Assunto: RE: {SPAM?} Protecting Hydrology Science from REINVENTION

Mr. Silva, has anyone ever called you a nutcase?

Are people out to get you?

Are you having some trouble keeping up with your medications?

---------------------------------
Steven V. Owen
University Professor Emeritus
Educational Psychology
---------------------------------

Dr. Owen, my medicine is a bit bitter than that one swallowed by Albert Einstein by just stretching his tongue:

http://youtu.be/E3d-JRg28p8

https://youtu.be/czv2OiiC5wA

_____________________________________________________________

This email from an Emeritus Faculty of Educational Psychology provided valuable insights and feedback showing how deep the academic community is compromised on scientific affairs in the US.They were supposed to know that Darcy’s Law on Hydraulic Conductivity is not written in the US constitution, but endorsed by Mother Nature.

_____________________________________________________________

Nobel Prize is IMPORTANT TO HUMAN KIND, as 50% is business, 40% politics, 5% bad science and 5% good science from an educated abstraction. Nobel Prize Nomination of Economic Science was introduced to pretend that Human Business could overlap nature functioning. THE US AS THE FIRST ECONOMIC POWER IN THE WORLD GRABBED TWO-THIRDS (411/621) OF NOBEL PRIZE NOMINATIONS FOR SCIENCE. Exploratory Analysis shows that the American scientific community has been violating Hydrology science in the Patenting System more than a century, leaving a gap huge enough for a new science Hydrotechnology. It seems that working with the Chemistry of explosives is far more profitable than the Hydrology of self-watering flower pots. Mr. Alfred Nobel, Arms Dealer, Merchant of Death, and Father of Dynamite, got 355 patents and Albert Einstein got 50 issued patents to portray top scientists claiming intellectual property rights. Obesity, Economic Melt Dow, COVID-19 tragedies, and now Reinvention Policy by USPTO are important evidence of American negligence to science misbalance with Nature.

How much NATURE endorses the Economy and Politics? Sunlight and rain come to us FREE OF CHARGE, regardless of BOUNDARIES, making the Economy not a science, but a distorted human affair as basic Laws of offer and demand is being replaced by GREED and FEAR. Likewise, recent wars in Ukraine and Israel show us that Politics can’t be science, but a wicked manipulation on human issues wasting innocent lives and spoiling the landscape for weaponry industry profit and disguised interest as Homo sapiens misses simple rationality.

In my neighborhood, I saw the Scientific Police taking pictures of swings I installed on trees for children in the Park during the COVID-19 pandemic lock down. Society try to employ the word SCIENCE for POWER, but there is a misunderstanding as scientific principles claim TRANSPARENCY and HONESTY. Nature is in charge of SCIENCE as there is no POLICE to enforce Nature LAWS. Even religion try to use Scientology for credibility. I like the simple conception that God = Nature. However, Nature writes no books, promises no lands, no life after death, no war or death in name of a divine. In around 4 billions of years of our planet, it seems that we got no aliens to affect our evolution. Most probable we are not leaving our home until the end in 4 to 6 billions of years. Human challenge is to keep nuclear weapons safe, cropping soils, mining our minerals and preserve our home in balance with nature functioning, making our blue planet good for all humans.

What we see in the universe is just for light travelling.

It seems that few scientists do understand the meaning of their titles PhD as Philosophy Doctor coming from Philosophy of Science (Epistemology, Metaphysics, Logics, and History of Science).

_____________________________________________________________

The Conspiracy

_________________________________________________________________

Princeton University – Plundering of Science

Is it possible to reinvent a ‘scientific breakthrough’ in Hydrology if you are a Physicist having no expertise in the issue?

Who cares?

I got my PhD at a famous place Penn State that let boys be raped in the locker rooms more than a decade. Bill Clinton then President was on my commencement saying we would be inventing new technologies never imagined before. He did not mention about fixing government malfunctioning violating science in the core! While money was poring and fame was high Joe Pa and Graham Spanier did not budge to protect a sound functioning of society as it seems to be a major trend around . . . after all who cares about disadvantaged boys and even less for science?

USPTO Reinvention Policy

Inventors owning US patents only collect money if they can afford court fees suing violators reinventing their ideas over and over sometimes by flawed patents from lay inventors and wealthy parties.

What does it means?

It means that inventions granted American patents might collect rewards if the inventor can afford 2 to 5 million dollars for suing a continuous reckless patent infringement from wealthy parties colluding with US Officials.

American patents are becoming useless if the inventor cannot afford steep court fees on continuous litigations.

Who takes advantages by the Reinvention Policy?

government and Law Firms profit high by reinvention policy spoiling the patenting system and harming inventors that cannot feed such swindle.

Who are the Patent Examiners and what is their technical-scientific background?

USPTO confirmed having no single Patent Examiner with background in Hydrology among around 6,000 examiners. So, Patent Examiners are simply not known in the art for judging the issue granted!

I told Mr. Obama early 2011 not to dishonor Hydrology this way . . . http://hydrotechnology.blogspot.com.br/

Corporation Pillage on Inventions

Ecolab: Flawed Violations by wealthy corporations

Ecolab employs more than 26,000 people with more than $6 billion in global sales. I sent letters to Ecolab, to Kinney & Lange, P.A the patent law firm, and to USPTO about violating my patent rights with a flawed one that even does not work.

The fluid only drops after crossing the water table as portrayed in the arrow reference because the ‘wick’ needs to cross the boundaries between Unsaturated and Saturated Hydraulic Zones for water to drop. The aggravation is that after I notified all parties in written about the violation of IP rights and scientific flaws more patents applications were filed and issued US 7,285,255 and US 7,670,551 . This is just unacceptable. What kind of protection anybody can get by ignoring IP rights and scientific literature?

A video can show it in 5 minutes what lay people missed in a patenting approval.

Hydrology Science is being shamefully ignored in the Patenting System with flawed patents that violate common knowledge from scientific literature and issued patents. It seems that sometimes the Patent Examiner (US pat. 7,285,255) violating science and issued patents is a director meaning that lay people handling Hydrology at USPTO is a critical bias going up in the chain of power by people that are overstepping Ethical grounds beyond their due expertise. This was not a simple mistake by a junior Patent Examiner since Ms. Gladys Corcoran had issued 202 patents so far.

REINVENTION POLICY BY USPTO: When a Patent Supervisor and Director (Ms Gladys Corcoran) issues a flawed patent US 7,285,255 hurting Hydrology and my issued patents it points the tip of the iceberg portraying a wicked reinvention policy by USPTO.

Ms Gladys J. P. Corcoran and Mr. Sean E Conley Primary and Assistant Examiner four months earlier issued 7,244,398 (July 17, 2007) citing my issued patent 6,766,817 meaning that they were aware of the new conceptions in hydrodynamics disclaimed in the art if they were knowledgeable in the art of Hydrology. Consequently the flaw issued at US 7,285,255 (October 23, 2007) was not a simple consequence of careless professionals working off their expertise boundaries ignoring advanced Hydrology already on literature and updated by 6,766,817, very likely un underlying consistent bias breaking the Law on Ethic boundaries..

Mr. Gregory Morse a Patent Commissioner answered my letter saying that there is a Law stating that the drawing dimensions does not need to represent the real dimensions of the device. I replied saying that I learned in High School about scale that all details are represented in the same proportional ratio and that the scientific flaw of (US pat. 7,285,255) takes places at any scale like parallel lines that never meet each other at any scale employed.

I got PhD in Soil Science/Spatial Applied Hydrology with a deep background in Remote Sensing and GIS and now I have my ‘scientific breakthrough’ being violated by lazy patents from people that their background is lower than High School standards.

‘It seems that Mr. Clinton wasted his time on my commencement.’

Roche employs about 67,000 people around the world and has about 44 billion dollars revenue annually. A group of researchers at Roche Diagnostics was filing dozens of patent applications trying to develop the spatial geometry of a channel on lancets to conduct blood for glucose test.

This left figure shows that Roche does not employ any Hydrologist or Soil Scientist to understand the deep functioning of fluids moving on porous systems, even less the rounding geometry. So, they learned with my patent, copied it and poorly reinvented it certainly bribing and corrupting US officials, as well as ignoring my pleas for HONESTY under the Law. The violation is so despicable that the Patent Examiner Mr. Max Hindenburg allowing the violation had already cited my patent earlier allowing 7,377,904 on May 27, 2008 and the technical background is so poorly handled that the Hydrology scientific community is going to become mesmerized by such nuisance

I told Roche and put more than 4,000 of their emails on my blog (http://roche-tubarc.blogspot.com ) that If they have this power to bribe US officials on money making, they should be smarter and bribe people at the Treasure Office by printing the bills. Stealing my invention poorly is just impossible as knowledge cannot be recreated even less by those ones not known in the art missing critical background and expertise.

Carefusion Corporation employs around 16,650 people and has an annual budget of about 4 billion dollars revenue. It filed seven patents poorly claiming the same geometry of Tubarc.

US 20130255672 - TRANSPORTING LIQUID IN A RESPIRATORY COMPONENT

Abstract

A respiratory component coupled with a breathing circuit, the respiratory component including at least one groove disposed upon a surface of the respiratory component, wherein the respiratory component is not a heater wire.

Claims

1. A respiratory component comprising: a liquid transporting device configured for transporting a liquid from a first region to a second region, wherein said liquid transporting device is disposed on a surface of said respiratory component and is not disposed on a heater wire.

2. The respiratory component of claim 1, wherein said liquid transporting device comprises: at least one groove disposed upon said surface of said respiratory component, wherein said at least one groove is configured for wicking up liquid from said first region and transporting said liquid to said second region.

Illumina, Inc.: They got the same geometry as Tubarc twice. As a scientist I am glad to have created something that is really good and important to human kind, but I was expecting a reward from it so I could invest in my research project. It means that the Intellectual Property system is failing to scientists and inventors on their dedication and hardship.

Pledging Illumina, Inc. to Respect Hydrology Science, Ethics, and the Law

8,765,486 Methods and systems for controlling liquids in multiplex assays

Abstract

A fluidic device for conveying liquid to a well of a microplate. The device includes a support structure configured to be mounted along the microplate. The device also includes a microfluidic tube coupled to the support structure. The tube has an inlet, an outlet, and an open-sided channel that extends longitudinally therebetween. The tube has a cross-section that includes an interior contour with a gap therein. The gap extends at least partially along a length of the tube. The tube is configured to convey liquid to the well of the microplate when the tube is held in a dispensing orientation.

Claims

1. A fluidic device for conveying liquid to a well of a microplate, the device comprising: a support structure configured to be mounted along the microplate; and a microfluidic tube coupled to the support structure, the tube having an inlet, an outlet, and an open-sided channel that extends longitudinally therebetween, the tube having a cross-section that includes an interior contour with a gap therein, the gap extending at least partially along a length of the tube, the tube being configured to convey liquid to the well of the microplate when the tube is held in a dispensing orientation.

Academic Pillage on Hydrology Science

UCONN: I, II, III, IV, V, VI, VII, VIII, IX, X, XI, XII, XIII, XIV

Academic Dishonoring of a scientific breakthrough

Dr. Amir Faghri and Dr. Zhen Guo working at the former Fuel Cell Center at the University of Connecticut believed that Hydrology from their Library can be ignored as well as my patent rights at USPTO when issuing US 7,625,649 ‘Vapor feed fuel cells with a passive thermal-fluids management system’ below. It was sent many letters requesting IDS of US 6,766,817 to many faculties and Intellectual Property management team at Univ. of Connecticut. Nobody there felt any urge to respect neither Classical Hydrology nor already issued patents on the subject. There is no doubt about breach of Ethics and breaking the Law by reinventing something already invented.

It seems that Mechanical Engineers insist on working with fluids having a private Hydrology on their own ignoring Classical Hydrology from old textbooks. US 6,766,817 not only designed the interplay between Hydraulic Zones allowing self-sustaining reversible flow, but also it gauged Unsaturated Hydraulic Conductivity as 2.18 mm/s, besides Tubarc as an enhance microporosity geometry for fluid conduction.

Looking at the drawings I have a deep feeling that it was a straight lousy copycat by a PhD faculty showing arrogance and how stupid he can be by ignoring a ‘scientific breakthrough’.

Is US 6,766,817 a ‘scientific discovery’?

I believe so because so far only 24 issued patents had mentioned Unsaturated Hydraulic Conductivity while wick/wicking from lay people was mentioned in 26.852 issued patents on Mar 24, 2011.

Univ. of Maryland: I, II, III

Collapsing Scientists – Renowned scientists are developing know-how on fluidic devices ignoring basic understanding on Hydrology principles and IP rights on issued patents by USPTO. The

pat. Appl. 20140191438 - Microfluidic Devices and Methods of Fabrication, has neither a single quotation on ‘hydrology’ nor any Hydrology reference complying with the main science of fluids.

hy•drol•o•gy - The scientific study of the properties, distribution, and effects of water on the earth's surface, in the soil and underlying rocks, and in the atmosphere.

How can any scientist address fluidic devices without knowing Hydraulic Conductivity (K) on Hydrodynamics? Hydraulic Zones? Hydraulic Gradient?

Hydraulic Conductivity (K) = volume / area / time

Scientific Flaw

They are not aware of employing ‘Unsaturated Hydraulic Siphon” to displace fluids by a hydraulic gradient on the interplay between Hydraulic Zone when fluids can move reversibly by unsaturated flow taking advantage of molecular connectivity of fluid dynamics.

SUNNY: I, II, III, IV

Dr. Gorfinkel Mathematician/Physicist from SUNY (

8,231,844) reinvented Tubarc (US 6,766,817) having no single paragraph addressing Hydrology Science on her issued patent. I am curious on how much Hydrology is taught in Mathematics and Physics courses to give professionals required background to handle such issue.

Title: Method and device for manipulating liquids in microfluidic systems. Assignee: The Research Foundation Of State University Of New York (Albany, NY)

Carnegie Mellon I, II, III, IV, V

Complex Engineering on hydrodynamics is confused on geometries between squares and circles!

‘Dr. Fedder, PhD, is proposing a squared geometry in order to control fluid dynamics employing ‘Capillary Action’, which comes from the cylindrical structure conception – capillary’

How much brain power is required to realize that ‘capillary action’ is a cylindrical geometric conception to capture unsaturated hydraulic flow when the solid surface of porosity pulls fluids upward against gravity having a suction or negative hydraulic flow? Frankly speaking can any capillary be squared? It seems that Nature opted for rounded geometries since the beginning making the sun, earth, cells, veins, trunks, etc, all rounded and rounded. Dr. Fedder empty skull is also rounded!

BTW – Dr. Fedder did not allow his patent application be published and it was issued seven years afterwards!

Carnegie Mellow is just raping science and shamefully cheating on Academic Affairs in collusion with USPTO shameful reinvention policy. Dr. Gary K. Fedder the Director of the Institute for Complex Engineered Systems (ICES) got B.S. and M.S. from MIT in 1982 and 1984,obtaining in 1994 PhD at the University of California at Berkeley.

UC SANTA BARBARA I, II, III

US Pat. Application 20130327504 - TITANIUM-BASED THERMAL GROUND PLANE assigned to THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA - December 12, 2013.

The word wick is not portrayed in any Hydrology textbooks because fluid moves in response to a Hydraulic gradient far more complex than oil lamps and candles requiring no flames at all. The patent application from University of California mentions the word wick 128 times while the word Hydrology is ignored shamefully by scientists pretending to know what they are doing.

Princeton University I, II, III, IV

Dr. Austin is a Professor of Physics trying to reinvent tubarc (US 6,766,817) ignoring Hydrology shamefully.

If for a lay person in Hydrology like a Physicist or a Mathematician channels or trenches are just containment structures, but for a Hydrogeologist it is a conceptional continuous pore connectivity to favor higher level of anisotropic unsaturated hydraulic flow providing higher reliability and enhanced control of hydrodynamic properties for molecular connectivity on porosity systems. Capillarity based on tube theory does not allow a making of a porosity for having one directional flow inside the tube. Tubarc (tube+arc) allows multidirectional flow with prevailing anisotropic longitudinal flow. It looks like simple and obvious, but Nature designed biological porosity with channels and perforations to be sure that fluids flow moving substances around as needed.

Tubarc = alignment of pores longitudinally bearing high geometrical pattern for fluid conduction harnessing Unsaturated Hydraulic Flow and producing an enhanced porosity structure with high control on void ratio and reversible fluid displacement in the interplay between Hydraulic Zones.

Sometimes we must refrain from saying how stupid somebody is simply for not bearing enough brain power from such comprehension. Nature endows brain to all human beings, but their deep functioning varies a lot. Perhaps intelligence goes far beyond IQ levels and can be perceived on expanding waistlines to portrait an understanding if brain resources are applied to self-maintenance on a modern different landscape we are molding day by day that challenge our deep physiology even more from the past we came from.

They are violating my IP rights simply for not having enough brain power to comprehend the principles and even less about honesty molding values for respect and dignity. Indeed intelligent people do not do such a thing, as they know deeply about coherence, harmony, logics, and values! I believe that a smart man would never dare to cheat Albert Einstein achievements.

Robert H. Austin received his B.A. in Physics from Hope College in Holland MI and his Ph.D. in Physics from the University of Illinois Champaign-Urbana in 1976. He was a post-doc at the Max Planck Institute for Biophysical Chemistry from 1976-1979 and has been at Princeton University in the Department from Physics from 1979 to the present, achieving the rank of Professor of Physics in 1989.

Position: Professor

Title: Professor of Physics.

Office: 122 Jadwin Hall

Phone: 609-258-4353

Email: austin@princeton.edu

Homepage: http://www.princeton.edu/austingroup/

US Pat Appl 20140206555 - Nanochannel Arrays and Their Preparation and Use for High Throughput Macromolecular Analysis

Abstract

Nanochannel arrays that enable high-throughput macromolecular analysis are disclosed. Also disclosed are methods of preparing nanochannel arrays and nanofluidic chips. Methods of analyzing macromolecules, such as entire strands of genomic DNA, are also disclosed, as well as systems for carrying out these methods.

Claims

1. A method of analyzing at least one macromolecule, comprising the steps of: transporting at least one macromolecule in a fluid sample into a nanochannel, such that the at least one macromolecule is in an elongated state within the nanochannel; maintaining the at least one macromolecule in an elongated state within a region of the nanochannel having a substantially constant width; detecting at least one signal from the at least one elongated macromolecule within the nanochannel; and correlating the detected signal to at least one property of the at least one macromolecule.

2. The method of claim 1, wherein the at least one macromolecule is transported into the nanochannel by applying an electric current.

3. The method of claim 1, wherein the trench depth of the nanochannel is less than about 200 nanometers.

4. The method of claim 1, wherein the step of maintaining the at least one macromolecule in an elongated state within the nanochannel is achieved via confinement of the at least one macromolecule within the nanochannel.

5. The method of claim 1, wherein the nanochannel comprises dimensions that are at most the same order of the persistence length of the macromolecule.

6. The method of claim 1, wherein the step of transporting the at least one macromolecule into the nanochannel such that the at least one macromolecule is in an elongated state occurs in a first region of the nanochannel and the step of detecting the at least one signal is performed in a second region of the nanochannel.

7. The method of claim 1, wherein the step of maintaining the at least one macromolecule in an elongated state within the nanochannel is achieved without the requirement of shear force acting on at least one macromolecule.

8. The method of claim 1, wherein the nanochannel is in the material of a surface.

9. The method of claim 1, wherein the nanochannel is surmounted by sealing material to render the nanochannel at least substantially enclosed.

16. The method of claim 1, further comprising the step of illuminating the at least one macromolecule within the nanochannel.

17. The method of claim 10, wherein the sealing material is optically transparent, and wherein the signal is transmitted through the optically transparent sealing material.

18. A method of maintaining at least one macromolecule in an elongated state, comprising the steps of: transporting at least one macromolecule in a fluid sample into a nanochannel, such that the at least one macromolecule is in an elongated state within the nanochannel; and maintaining the at least one macromolecule in an elongated state within a region of the nanochannel having a substantially constant width.

19. The method of claim 18, wherein the at least one macromolecule is transported into the nanochannel by applying an electric current.

20. The method of claim 18, wherein the trench depth of the nanochannel is less than about 200 nanometers.

21. The method of claim 18, wherein the step of maintaining the at least one macromolecule in an elongated state within the nanochannel is achieved via confinement of the at least one macromolecule within the nanochannel.

22. The method of claim 18, wherein the nanochannel comprises dimensions that are at most the same order of the persistence length of the macromolecule.

23. The method of claim 18, wherein the step of maintaining the at least one macromolecule in an elongated state within the nanochannel is achieved without the requirement of shear force acting on at least one macromolecule.

24. The method of claim 18, wherein the nanochannel is in the material of a surface.

25. The method of claim 18, wherein the nanochannel is surmounted by sealing material to render the nanochannel at least substantially enclosed.

[0002] The present invention relates to a nanochannel array. The present invention also relates to a method of preparing nanochannel arrays. The present invention also relates to nanofludic chips containing nanochannel arrays. The present invention also relates to a system suitable for high throughout analysis of macromolecules. The present invention also relates to a method of analyzing at least one macromolecule by using a nanochannel array.

[0003] In the newly emerging field of bioanotechnology, extremely small nanofludic structures, such as channels, need to be fabricated and used as arrays for the manipulation and analysis of biomolecules such as DNA and proteins at single molecule resolution. In principle, the size of the cross sectional area of channels should be on the order of the cross sectional area of elongated biomolecules, i.e., on the order of 1 to 100 square nanometers, to provide elongated (e.g., linear, unfolded) biomolecules that can be individually isolated, yet analyzed simultaneously by the hundreds, thousands, or even millions. Likewise, it is also desirable that the length of the channels should be long enough to accommodate the longest of macro-molecules, such as an entire chromosome, which can be on the order of 10 centimeters long (e.g., chromosome 1 of the human genome having 250 million base pairs). The present inventors and others have recently been concerned about such problems and their possible solutions, as reported in: O. Bakajin, et al, Anal Chem, 73 (24), 6053 (2001), J. O. Tegenfeldt, et al, Phys. Rev. Lett. 86 (7), 1378 (2001), J. Han et al., Science 288, 1026 (2000), and S. R. Quake et al., Science 290 (5496), 1S36 (2000).

[0004] It is important to efficiently and reliably construct arrays of many thousands, or even millions of channels in an array for the simultaneous isolation and analysis of up to thousands or millions of individual macromolecules. Such large arrays of isolated macromolecules could, in principle, be analyzed with presently available two-dimensional area detectors, such as charge-coupled devices (CCDs). Together with automated data-processing collection and image analysts software, the simultaneous characterization of up to thousands or millions of micromolecules would be an extremely powerful tool for macromolecular analysis, such as population distribution analysis of macromolecular size, chemical composition, and DNA sequencing.

[0005] Because individual macromolecules could in principle be isolated and analyzed in a single channel, heterogeneity of a sample containing a multitude of macromolecules can be readily discerned. This would be particularly useful for identifying single nucleotide polymorphisms (SNP) on a single chromosome. In contrast, traditional population based assays require time-consuming DNA amplification methods to prepare multiple copies of a nucleic acid macromolecule to carry out SNP analysis. If available, a chromosomal analysis system incorporating nanochannel arrays could perform SNP analysis much more quickly than any method presently available.

[0006] Nanochannel arrays having the proper dimensions for carrying out the simultaneous isolation and analysis of a multitude of elongated macromolecules have been heretofore unavailable. Accordingly, there is an urgent need to provide nanochannel arrays having at least three key dimensional qualities: (1) the channels should have a sufficiently small dimension to elongate and isolate macromolecules; (2) the channels should have a sufficiently long dimension to permit the instantaneous observation of the entire elongated macromolecule; and (3) a high number of channels should be provided to permit the simultaneous observation of a high number of macromolecules. In addition, it would be desirable for the elongated and isolated macromolecules to remain indefinitely in such a state at ambient conditions even after the field which is used to transport the macromolecules into the channels (e.g., electric field) is turned-off. This feature would permit the macromolecules to be analyzed with techniques that require times longer than the residence time of the macromolecules under the influence of the field. This feature would also permit the analysis of macromolecules without having to subject them to a field.

[0007] Methods for analyzing macromolecules (e.g., polymers) have been previously disclosed, however none uses a nanochannel array having the three key dimensional qualities as described supra.

U.S.

Pat. No. 5,867,266 discloses a micro optical system having a plurality of coplanar micron-to-millimeter scale sample channels prepared using photolithography and an artificial gel material comprising a multiplicity of pillar structures in each micron-to-millimeter wide sample channel. The large channel width makes this system unsuitable as a nanochannel array.

[0008] Likewise, methods for analyzing macromolecules (e.g., polymers) by isolating them in channels more narrow than this disclosed in U.S. Pat. No. 5,167,266, however none uses a nanochannel array having the three key dimensional qualities as described supra. In WO 00/09757, several of the inventors of the present patent application disclose a system for optically characterizing single polymers that are transported in a straightened form through a channel. In

U.S.

Pat. No. 6,355,420, a system is disclosed for analyzing polymers that are transported in a straightened form through a plurality of (at least 50) channels. While both of these disclosures are directed towards analysis of single macro-molecules aligned in one or more channels, neither of these documents discloses the simultaneous observation of a high number of macromolecules in a multitude of channels.

[0009] Thus, there remains the problem of providing suitable nanochannel arrays that are useful in a variety of macromolecular analysis. Methods for analyzing macromolecules (e.g., polymers) by isolating them in a narrow channel have been previously disclosed, however none uses a nanochannel array having the three key dimensional qualities as described supra, primarily because, until now, fabrication techniques for constructing such a nanochannel array were not available.

[0010] In creating ultra-small nanofluidic structures, e.g., for single biomolecule analysis, at least two problems need to be solved: reduction of size and creation of sealed fludic channels. As reported by one of the present inventors, NIL is a parallel high-throughput technique that makes it possible to create nanometer-scale-features over large substrate surface areas at low cost. (S. Y. Chou et al. Appl. Phys. Lett 67 (21), 3114 (1995) and S. Y. Chou et al. Science 272, 85 (1996)) Current sealing techniques such as wafer bonding (M. Stjernstrom et al., J. Micromech. and Microeng. 8 (1), 33 (1998)), and soft elastomer sealing (H. P. Chou et al. Proc. Nat. Acad. Sci. USA 96 (1), 11 (1999), are suitable for relatively large planar surfaces and provide an effective seal. Wafer bonding requires an absolutely defect tree and flat surface, and elastomer sealing suffers from clogging due to soft material intrusion into the channels. Within extremely small confining structures biological samples are also much more sensitive to issues such, as hydrophobicity and the homogeneity of the material constructing the fluidic structure.

[0011] Recently developed techniques using "place-holding" sacrificial materials such as polysilicon (S. W. Turner et al. J. Vac. Sci, and Technol. B. 16(6), 3835 (1998)) and polynorbornene (D. Bhusari et al., J. Microelectromech. Syst. 10 (3), 400 (2001)) have gained popularity to create sealed small, hollow fludic structures. However, steps needed in removing the sacrificial materials such as heating the substrate up to 200-400.times. or wet etching limits the use of certain materials and downstream fabrication processes.

[0012] As provided herein, the present invention achieves the goal of providing nanochannel arrays suitable for performing high throughput macromolecular analysis. Interferometric lithography (IL), nanoimprint lithography (NIL), and non-isotropic deposition techniques are used to prepare nanochannel arrays having hundreds of thousands to more than a million enclosed channels having the desired key dimensions across the surface of a silicon wafer substrate.

[0013] In one aspect of the present invention, there are provided nanochannel arrays including a surface having a plurality of channels in the material of the surface, said channels having a trench width of less than about 150 nanometers and a trench depth of less than 200 nanometers; at least some of the channels being surmounted by sealing material to render such channels at least substantially enclosed.

[0014] In a further aspect of the present invention, methods of preparing nanochannel arrays are disclosed, which include the steps of: providing a substrate having a surface; forming a plurality of channels in the material of the surface; and depositing a sealing material on the plurality of channels to surmount the plurality of channels to render such channels at least substantially enclosed, the substantially enclosed channels having a trench width of less than 150 nanometers and a trench depth of less than 200 nanometers.

[0015] In another aspect of the invention, there are provided nanofluidic chips including; a) nanochannel array, including: a substrate having a surface; a plurality of parallel channels in the material of the surface, said channels having a trench width of less than about 150 nanometers and a trench depth of less than 200 nanometers; at least some of the channels being surmounted by sealing material to render such channels at least substantially enclosed; at least some of the channels are capable of admitting a fluid; b) at least one sample reservoir is fluid communication with at least one of the channels, said sample reservoir capable of releasing a fluid; and c) at least one waste reservoir in fluid communication with at least one of the channels, said waste reservoir capable of receiving a fluid.

[0016] In yet another embodiment of this invention, there are provided systems for carrying out analysis. In exemplary embodiments, these include: A) a nanofludic chip, including: a) nanochannel array, including: a substrate having a surface, a plurality of parallel channels in the material of the surface, said channels having a trench width of less than about 150 nanometers and a trench depth of less than 200 nanometers; at least one of the channels being surmounted by sealing material to render such channels at least substantially enclosed; at least one of the channels capable of admitting a fluid; and b) at least one sample reservoir in fluid communication with at least one of the channels, said sample reservoir capable of releasing a fluid; and B) a data processor.

[0017] In another embodiment, methods of analyzing at least one macromolecule are described which, for example, include the steps of: providing a nanofluidic chip, including: a) nanochannel array, including; a surface having a plurality of parallel channels in the material of the surface, said channels having a trench width of less than about 150 nanometers and a trench depth of less than 200 nanometers; at least one of the channels being surmounted by sealing material to render such channels at least substantially enclosed; at least one of the channels capable of admitting a fluid; b) at least one sample reservoir in fluid communication, with at least one of the channels, said sample reservoir capable of releasing a fluid containing at least one macromolecule; providing the at least one sample reservoir with at least one fluid, said fluid comprising at least one macromolecule; transporting the at least one macromolecule into the at least one channel to elongate said at least one macromolecule; detecting at least one signal transmitted from the at least one elongated macromolecule; and correlating the detected signal to at least one property of the at least one macromolecule.

[0018] Cartridges including a nanofluidic chip in accordance with this invention are also disclosed herein. Such cartridges are capable of being inserted into, used with and removed from a system such as those shown herein. Cartridges useful with analytical systems other than the systems of the present invention are also comprehended by this invention.

[0019] FIG. 1 illustrates a cross-section of a nanochannel array having substantially enclosed channels.

[0020] FIG. 2 illustrates a cross-section of a nanochannel array having completely enclosed channels and having sealing material deposited in the channels.

[0021] FIG. 3 is a scanning electron micrograph of a nanochannel array having parallel linear channels and open channel ends.

[0022] FIG. 4 illustrates a schematic of a process for depositing sealing material into the channels.

[0023] FIG. 5 illustrates a nanofludic chip.

[0024] FIG. 6a is a scanning electron micrograph of the substrate used in Example 4 prior to sealing with silicon dioxide.

[0025] FIG. 6b is a scanning electron micrograph of the nanochannel array of Example 4 obtained after sealing the substrate with silicon dioxide.

[0026] FIG. 6c is a scanning electron micrograph (top view) of the nanochannel array of Example 5.

[0027] FIG. 6d is a scanning electron micrograph (top view) of the nanochannel array of Example 4.

[0028] FIG. 7a is a scanning electron micrograph of the substrate used in Example 1 prior to sealing with silicon dioxide.

[0029] FIG. 7b is a scanning electron micrograph of the nanochannel array of Example 1 obtained after sealing the nanochannel array in 7a with silicon dioxide.

[0030] FIG. 7c is a scanning electron micrograph of the substrate used in Example 2 prior to sealing with silicon dioxide.

[0031] FIG. 7d is a scanning electron micrograph of the nanochannel array of Example 2 obtained after sealing the nanochannel array of 7c with silicon dioxide.

[0032] FIG. 7e is a scanning electronmicrograph of the substrate used in Example 3 prior to sputtering with silicon dioxide.

[0033] FIG. 7f is a scanning electron micrograph of the nanochannel array of Example 3 obtained after sputtering the nanochannel array in 7e with silicon dioxide.

[0034] FIG. 8a illustrates a sealed channel having a nanoslit in an opaque layer across the bottom of a channel.

[0035] FIG. 8b illustrates a sealed channel having a nanoslit in an opaque layer across the sealing layer, which is oriented perpendicular to the long axis of a nanochannel.

[0036] FIG. 9a shows scanning electron micrographs of the substrate (left and bottom) and a of the sealed nanochannel array (right) used in Example 14.

[0037] FIG. 9b is the image obtained tram the CCD of the 48.5 kb lambda, phage genome (shorter) and 168 kb T4 phage genome (longer) of Example 14. Inset; Plot of genome size versus macromolecular contour length.

[0038] FIG. 9c shows a nanochannel array simultaneously elongating, separating, and displaying a plurality of DNA macromolecules ranging in size from 10 kb to 196 kb.

[0039] FIG. 10 illustrates a system for analyzing macromolecules using a nanofluidic chip.

[0040] One aspect of the present invention encompasses a nanochannel array having a plurality of channels that are substantially enclosed. As shown in FIG. 1, the nanochannel array 108 has a surface 102 that contains a plurality of channels 104 in the material of the surface 106. The channels 104 have a wall 110, and a channel center 112. The distance between the wall surfaces 110 inside a channel 104 that are perpendicularly opposite to the channel center 112 is defined as the trench width. The channels 104 are surmounted by a sealing material 188 that renders the channels 104 at least substantially enclosed.

[0041] In one embodiment, the channels 104 will not be completely enclosed and will typically have a sealing material 108 directly above the channel center 112, providing an opening in the sealing material to the channel. The opening may have a variety of shapes. The size of the opening is defined as the minimum distance spanning the opening above the channel center 112. In such embodiments, the size of the opening is less than the trench width, and is typically less than 1/2 of the trench width, more typically less than 1/3 of the trench width, and most typically less than 1/4 of the trench width, in other embodiments the channels can be completely enclosed, having sealing material completely covering the top of the channel and having no opening in the sealing material. In certain embodiments of the present invention, sealing material 108 can extend over the wails 110 and the bottom of the channels 104, as shown in FIG. 2. In such embodiments, the trench width is defined as the distance from the surfaces formed by the sealing material adjacent to the walls 114.

[0042] In the present invention, the trench width is typically less than 150 nanometers, more typically less than 100 nanometers, and even more typically less than: 75, 50, 25, and 15 nanometers. In certain embodiments the trench width is about 10 nanometers, in the present invention, the trench width is at least 2 nm, and typically at least 5 nm.

[0043] In the present invention the channels are at least substantially enclosed. "At least substantially enclosed" means that the channels are completely enclosed; or have an opening in the sealing material that is smaller than 1/2 the trench width, or have both completely enclosed channels and openings.

[0044] Channels that are completely enclosed have a trench depth that is defined as the distance between the surface of the solid material at the bottom of the channel below the channel center 112 to the sealing material above the channel center 112. Embodiments in which the channels having an opening have a trench depth defined as the distance from the surface of the solid material at the bottom of the channel below the channel center to the position of the opening where the opening size is measured. If the opening has more than one position where a minimum distance can be measured then the position of the opening is the one that is closest to the bottom of the channel 104.

[0045] In the present invention, the trench depth is less than 200 nm, in certain embodiments, the trench depth is typically less than 175 nm, and more typically less than 150 nm, 125 nm, 100 nm, 75 nm, 50 nm, and 25 nm. In certain embodiments the trench depth is about 1-5 nm. In certain embodiments the trench depth is at least 2 nm, typically at least 5 nm, and more typically at least 10 nm.

[0046] In the present invention, the nanochannel arrays can be formed in a substrate, such as a silicon wafer substrate, using a variety of fabrication methods as described below. In one embodiment, the nanochannel array has a plurality of parallel linear channels across the surface of substrate as illustrated by the scanning electron micrograph in FIG. 3.

[0047] In certain embodiments, the nanochannel arrays have at least one end of at least one of the channels can be in fluid communication with at least one reservoir. In these embodiments, at least one channel is connected directly with at least one reservoir. Alternatively, at least one channel can be connected with at least one reservoir via an interconnecting straight or curved microchannel (a channel having a width, height, or both larger than about a micron), or a channel is connected with at least one reservoir via an interconnecting nanopillar or micropillar array.

[0048] In certain embodiments, at least two ends of some of the channels are in fluid communication with at least one reservoir common to the channels. In these embodiments, at least two ends of some of the channels can be adjacent or not adjacent. These channels can be connected directly with at least one reservoir.

[0049] In certain embodiments, at least two channels can be connected with at least one reservoir via a common interconnecting straight or curved microchannel. Alternatively, at least two channels can be connected with at least one reservoir via a common interconnecting nanopillar or micropillar array.

[0050] In certain embodiments of the present invention, the nanochannel array has a plurality of channels that are in fluid communication with at least one sample reservoir common to at least some of the channels. By "a plurality of channels" is meant more than two channels, typically more than 5, and even typically more than 10, 100, 1000, 10,000 and 100,000 channels. In certain embodiments, one sample reservoir can be provided for all of the channels in the nanochannel array, thus the plurality of channels can be as large as the number of channels that are on the substrate, in a certain embodiments, 100 mm diameter substrates can have about 500,000 parallel linear channels having a periodicity of 200 nm, the periodicity being defined as the distance, between the middle of two adjacent channels.

[0051] In certain embodiments, the plurality of channels can be connected directly with at least one reservoir. The connections can be a common interconnecting straight or curved microchannel. In other embodiments, a plurality of channels can be connected with at least one reservoir via a common interconnecting nanopillar or micropillar array.

[0052] In certain embodiments of the present invention, the nanonanochannel array contains a plurality of channels that are in fluid communication with at least one waste reservoir. Although the plurality of channels is typically connected directly with at least one waste reservoir, more than one waste reservoir can also be provided. It should be appreciated that the waste reservoir can be used as a sample collection reservoir. Accordingly, multiple sample collection reservoirs can also be provided on nanochannel arrays. In these embodiments, a plurality of channels can be connected with at least one waste reservoir via a common interconnecting straight or carved microchannel as described earlier. Likewise, a plurality of channels can be connected with at least one waste reservoir via a common interconnecting nanopillar or micropillar array.

[0053] In certain embodiments of the present invention, the nanochannel array has a plurality of channels that are substantially parallel, in which the plurality of channels are substantially in the plane of the surface of the substrate.

[0054] In certain embodiments of the present invention, the nanochannel array can contain linear channels. Linear channels are adjacent channels that are substantially not interconnected.

[0055] In certain embodiments, the ends of the channels are capable of admitting a macromolecule in a fluid. By being capable of admitting macromolecule means that the channels have at least one opening large enough, to permit the passage of a macromolecule. While a variety of openings are envisages, typically such openings can be located at the ends of the channels or on the surface of the sealing material through openings in the sealing material. Openings in the sealing material can be provided by subsequent modification of the nanochannel arrays as provided below.

[0056] In certain embodiments of the present invention, the nanochannel array contains channels that are capable of transporting a macromolecule across their length. The nanochannel arrays can be fitted with a variety of components to affect macromolecular transport, examples of which include pressure or vacuum gradient drop across the channels, electroosmosis, and electrokinesis.

[0057] While not being bound to a particular theory, it is believed that macromolecules typically have a non-linear, three-dimensional conformation in space (e.g., linear polymers have a random coil conformation in their natural state). Accordingly, it is thermodynamically unfavorable for macromolecules to spontaneously elongate and enter channels directly from the environment due to the large free energy needed to reduce entropy. For example, a 169 kilobase T4 phage double stranded genomic DNA chains will form a Gaussian coil of radius of gyration Rg=(Lp/6).sup.1/2=700 nm in free solution, where L is its calculated contour length and p is the persistence length of about 50 nm.

[0058] In certain embodiments, the nanochannel array can contain channels capable of transporting at least one macromolecule across the length of channels, in which the macromolecule is in an elongated form. Such channels can have openings large enough to permit the entrance of the ends of the macromolecules. In certain embodiments, it is preferred that such channels also have trench widths and trench depths narrow enough to restrict the movement of the macromolecules to primarily one direction along the surface of the substrate. Preferably such channels are not interconnected.

[0059] In certain preferred embodiment, of the present invention, the nanochannel array is capable of transporting at least one biopolymer across the length of said channels. In these embodiments, the geometry of the channels permits the biopolymers to enter and move along the channels in at least one direction. Preferably, the channel surfaces are treated with a non-sticking agent, as described later, for preventing the adhesion of macromolecules, such as biopolymers, to the inside of the channels.

[0060] In other embodiments, it is preferred that the nanochannel array contains channels capable of transporting at least one unfolded biopolymer across the length of said channels. While not being bound by a particular theory, when the dimensions of the channels are apparently larger than the spatial conformation of the macromolecules, there is at least a partial amount of elongation of the macromolecules in the channels. When the dimensions of the channels are at the same order or below the persistence length, of macromolecules, such as 50 nm for DNA the macromolecules can be sufficiently elongated in an unfolded fashion inside the channels. When the dimensions of the channels fall in between the above-mentioned two scenarios, macromolecules can be partially elongated in these channels. In this case, the macromolecules can be folded, tangled, or both folded and tangled. While it is envisaged that any macromolecule can be transported in an unfolded fashion in the channels of the nanochannel array of the present invention, a variety of suitable unfolded macromolecules include RNA, DMA, denatured unfolded peptide chains, self assembled chemical polymers, and co-polymer chains, and other biopolymers, and combinations thereof.

[0061] In one preferred embodiment, the channel structures of the nanochannel arrays can be formed from linearly adjacent channel walls that span the substrate surface. In other embodiments, the channels can be formed from pillar structures, sell-assembled polymer structures, stacked membrane layers, and nanobeads (particles inside the channels).

[0062] The surface material of the nanochannel arrays can be formed from almost any substrate material, such as a conductive material, a semiconductor material, or a non-conductive material. Examples of conductive materials include metals such as aluminum, gold, silver, and chromium. Examples of semiconductive materials include doped silicon dioxide and gallium arsenide. Examples of non-conductive materials include fused silica, silicon dioxide, silicon nitride, glass, ceramics, and synthetic polymers. The foregoing is exemplarly only.

[0063] In the present invention, the surface of the nanochannel array is typically the surface of the substrate, such as the surface of a silicon wafer. Alternatively, the surface can be a film, such as one adjacently supported by a second substrate. Coating a material on to a second substrate can form films. A suitable coating process includes vapor deposition of a material onto a wafer.

[0064] In certain embodiments of the present invention, the nanochannel array includes at least one optically opaque material layer adjacent to the sealing material. The optically opaque material can be situated between the surface material and the sealing layer, it can be situated inside the channels, it can he situated on top of the sealing, material, or a combination of these. While almost any opaque material that can he deposited as a layer is possible in this embodiment, Aluminum is preferred. For certain embodiments, it is desirable that the opaque layer thicknesses are less then about 50 nm thick. For embodiments containing nanoslits useful for carrying out near-field imaging of the contents of the channels, it is desirable to prepare slits smaller than 50 nm that are etched through the deposited opaque layer but not through the transparent sealing material for maintaining the integrity of the adjacent (underneath) channel. Without being bound by a particular theory, the optically opaque layer functions as a blocking mask for high-resolution near-field excitation. Without being bound to a particular theory, aluminum is particularly preferred as an opaque layer because if has the highest known skin depth of any material at the given wavelength of the excitation light source rendering the smallest thickness of the blocking layer, hence the shortest distance between the slits and the possible target molecules in channels.

[0065] In certain embodiments of the present invention, the nanochannel array has at least one near field slit feature above at least one channel. Such slits should be fabricated as close (less than about 30 nm) to the channel as possible without compromising the integrity of the adjacent sealed channels. The thin wall of sealing material between slit opening and channels could be created by FIB milling or controlled material deposition.

[0066] In a further preferred embodiment, the nanochannel array contains sealing material adjacent to the channel bottom. Sealing material can be provided in channel bottom by depositing a suitable sealing material into the channels prior to or simultaneously with enclosing the channels.

[0067] The nanochannel arrays also preferentially have sealing material adjacent to the channel wall material. In this embodiment, the sealing material can reduce the trench width. This is particularly advantageous for preparing nanochannel arrays from a variety of substrate surfaces that contain channels wider than 150 nm in trench width and deeper than 200 mn in trench depth. In this embodiment, and as described below, sealing material can be deposited into channels by a variety of methods. One suitable method is E-beam evaporation, which creates a point source of material. In E-beam evaporation, a substrate is typically far away from the source compared to the size of the sample, and the angular distribution of the depositing material is very narrow. To achieve a non-uniform deposition the substrate is tilted at a specific angle. The channel walls partially block the deposition of sealing material (like a shadow), and most of the material is be deposited on the channel walls near the upper portion of the channel wall. Beyond a critical depth no deposition will occur as long as the substrate is tilted.

[0068] An alternative and preferred method to provide sealing material in the channels is sputter deposition. In sputter deposition, the sealing material is deposited at all angles, so the instant growth rate at any point on the surface depends on the percentage of the total target area within its line of sight, as is outlined in FIG. 4. Without being bound to a particular theory, sealing material, from a large target scarce 130 that is in close proximity to the substrate surface, can travel along a variety of trajectories (122, 124, 126, 127) and be deposited at different positions in the channels. Sputtering is typically med used because of the divergent nature of the material beam, thus resulting in the faster deposition of target material at the top part of the channels instead of at the bottom of the channels (i.e., surmounting the channel). In time, the sealing material near the top of the channels eventually completely encloses the channel, which prevents further deposition of sealing material into the channel. In one embodiment, the resultant sealing material in the channel results in a profile 128. Suitable sputtering systems are known in the art. A particularly suitable sputtering system has a 200 mm SiO.sub.2 target source which provides high surface coverage and uniformity across 300 mn substrate.

[0069] The lengths of the channels of the nanochannel array can have a wide range. The lengths of the channels can also he the same or different in the nanochannel array. For carrying out macro-molecular analysis using the nanochannel arrays as provided below, it is desirable that he channels are at least 1 millimeter (mm) longer. More typically, the length of the channels is greater than 1 centimeter (cm), and even greater than 5 cm, 15 cm, and 25 cm.

[0070] In another aspect of the present invention there is provided a method of preparing a nanochannel array, which includes the steps of forming a plurality of channels in the material of the surface of a substrate, and depositing a sealing material to surmount the plurality of channels to provide at least substantially enclosed channels. Substrates containing a plurality of channels preferably have a periodicity of 200 nanometers or less, which can be provided by interferometric lithography and nanoimprint lithography techniques, which are disclosed in U.S. Pat. No. 5,772,905, the complete disclosure of which is incorporated by reference herein. As described earlier, various types of materials can be used to prepare surfaces having a plurality of channels. Suitable substrates include semiconductors, dielectrics, polymers, self-assembled biofilm, membranes, metals, alloy, and ceramics.

[0071] The sealing material is preferably deposited to surmount the plurality of channels to render such channels at least substantially enclosed, the substantially enclosed channels having a trench width of less than 150 nanometers and a trench depth of less than 200 nanometers. By "surmount" is meant that the sealing material is preferentially deposited towards the top of the channels compared to the bottom of the channels, resulting in substantially enclosed channels, which is described above and in FIG. 4.

[0072] In certain embodiments of the present invention, the sealing material can be deposited using any of a variety of methods, including chemical vapor deposition, spin coating, film lamination, and thermo-evaporation. Preferably, the sealing material is deposited using electron-beam evaporation or sputtering.

[0073] In certain embodiments of the present invention, sealing material is deposited on substrate surfaces by a sputtering process at gas pressures typically less than about 20 mTorr, more typically less than 10 mTorr, and even more typically less than 5 m Torr. Sputtering is a process of driving molecules off a source target surface (such as SiO.sub.2) using energetic ionic bombardment. Atoms are knocked off from the source target and can be deposited on a variety of substrate surfaces, such as patterned silicon wafers. While not being bound to a particular theory, it is believed that as the gas pressure is reduced, there are fewer particles in the environment of the plasma sputtering chamber, which results in the depositing atoms to travel with fewer collisions before reaching the substrate surface; hence, a more anisotropic and faster deposition. At higher gas pressure such, as 30 mTorr, depositing atoms collide more frequently on their path to the substrate surface, hence a more divergent traveling angles and more isotropic, and slower deposition. At lower gas pressure with more anisotropic and last deposition, more depositing atoms can reach the bottom and lower part of the sidewalk of the trenches, causing relatively faster deposition of scaling material at she bottom and sidewalk comparing to the top of the trenches, this subsequently leads to smaller channel (trench) dimensions.

[0074] The aspect ratio of the trenches being sealed also affects the geometry of the final sealed void space. The higher the depth to width ratio, the less sealing material will be deposited near the bottom of the trench. The lower the depth to width ratio, the smaller and narrower the channel dimensions.

[0075] In one embodiment of carrying out the method of the present invention, at least one reservoir is provided to be in fluid communication with at least one end of at least one of the channels. Channels can be fabricated on the substrate using nanoimprinting and interconnecting structures of pillar arrays. Reservoirs can be defined using photolithography and subsequently pattern transferred to the substrate using reactive ion etching (RIE), chemical etching or FIB milling directly to create reservoirs in fluid communication with the channels. Auxiliary structures, such as nanochannels, for connecting the reservoirs to the channels can also be provided using these methods. Typical depth of the reservoirs and auxiliary structures is typically at least several hundreds of nanometers, preferably at least several micrometers deep.

[0076] In certain embodiments, it is desirable to provide an additional sealing step. A suitable additional sealing step includes application of a planar surface substrate to the top of the sealing material. Alternatively, reservoirs can be formed on the sealing planar substrate. Auxiliary fluid communicating structures larger than about a micron cart also be formed to connect to larger sample reservoir. A variety of schemes to connect reservoirs to the channels can be envisioned: at least 2 reservoirs can be provided in fluid communication with at least 2 separate channels; or at least 10 reservoirs are provided in fluid communication with at least 10 separate channels; or at least 96 reservoirs are provided in fluid communication with at least 96 separate channels; or at least 500 reservoirs are provided in fluid communication with at least 500 separate channels; or at least 5000 reservoirs are provided in fluid communication, with at least 100 separate channels; or combinations thereof.

[0077] In a preferred embodiment of the present invention, the method of preparing the nanochannel arrays is carried out using linear channel array substrates having a periodicity of less than 2.00 nm formed by nanoimprint lithography. In this embodiment, the linear channels have a trench width less than 100 nanometers and a trench depth less than 100 nanometers. In this embodiment, at least a portion of the sealing material is deposited using sputter deposition to provide sealing material adjacent to the channel wall material to narrow the trench width.

[0078] Varying the sealing material deposition parameters is also used to narrow the trench width of the channels. The deposition parameters can be varied to provide trench widths of typically less than 100 nanometers. As more material is deposited, trench widths can be narrowed to less than 75 nanometers, and even less than 50 nanometers, 25 nanometers, and 15 nanometers. Trench widths of about 10 nm can also be provided by the methods of the present invention. Typically, the resulting trench widths after deposition will be greater than 2 nm, and more typically greater than 5 nanometers. Trench depths of less than 175, 150, 125, 100, 75, 50 , and 25 nm can also be provided by the methods of the present invention. Trench depths of about 15 nm can also be provided. Typically, the trench depths will be at least 5 nm, and more typically at least 10 nm.

[0079] In another embodiment of the present invention, the method may also include the step of providing at least one near field slit feature above at least one channel. In this step, the sealing material is typically transparent, such as silicon dioxide, to permit spectroscopic detection of fluorescently labeled macromolecules, such as DNA, inside the channels. This permits the use of optical methods, such as near-field optical imaging, to analyze macromolecules in the channels. Nanochannel arrays suitable for near-field optical analysis can be modified to have nanoslits. As described above, the nanoslit above the channel is thin to permit sufficient evanescent excitation of the fluorescently-labled macro-molecules.

[0080] In one embodiment of the present invention, nanochannel arrays can be prepared having a sufficiently thin seal thickness suitable, for near-filed optical analysis of fluids in the channels beneath the sealing material. In one embodiment, channels having an opaque sealing material thicker than 100 nm can be modified using a suitable fabrication method to provide a nanoslit in the opaque sealing material.

channels to form at least one of; an insulating layer, a conducting layer, a hydrophilic layer, a hydrophobic layer, or combinations thereof. In this embodiment, fee layer thickness is typically less than half of the trench width.

[0083] In one embodiment, the dimensions, geometry, composition, or combinations thereof of the sealing material adjacent to the walls 114 can be modified and manipulated for corresponding samples being analyzed is the channels, in a particular embodiment. It is desirable to alter the surface properties of the sealing material adjacent to the wall 114 This is carried out by treating at least some of the channels with a surface modifying agent to alter the surfaces interior to said channels.

[0084] In one embodiment, surface-modifying agents are deposited in the channels to improve the transport of macromolecules into and through the channels. Surface-modifying agents are particularly useful where the internal dimensions (trench depth, trench height, or both) are less than about 50 nm. Surface-modifying agents can also reduce or increase hydrophobicity of the surfaces interior to said channels. Nonochannel arrays made according to the present invention can be contacted with solutions containing surface-modifying agents, such as by submerging the nanochannel array into such solutions. Suitable surface-modifying agents include polyethyleneglycol (PEG), surfactants, Bovin Serum Albumin (BSA) protein solution, surface non-specific binding saturation, and anti-protein sticking agents. Application of a pressure differential, such as vacuum, can be used to assist the treatment of the channels. Application of vacuum is also useful for degassing any fluids inside the channels.

[0085] In certain embodiments of the present invention, the surface-modifying agent counteracts the electroosmosis effects inside the channels. While not being bound to a particular theory, the electroosmosis effect is usually due to ionized acidic groups immobilized to the matrix (e.g., attached to the wall) inducing positively charged counter ions in the butler that migrate towards the negative electrodes, causing a bulk flow of liquid that migrates in the direction opposite to that of the negatively charged DNA. Accordingly, reducing electroosmosis effects helps charged macromolecules to be transported into and along the channels.

[0086] In one embodiment of the present invention, the channels can be at least substantially enclosed on the surface of the substrate and substantially open on the edges of the substrate. As described herein, the channels are at least substantially enclosed by controlling the deposition of the sealing material. In one embodiment, the channels are substantially open at the edges, which, are readily provided by cleaving or cutting the substrate to reveal the interior portion of the channels.

[0087] In one embodiment, the deposition of the sealing material completely encloses the plurality of channels, in this embodiment, the sealing layer is at least as thick as the atoms of the sealing material. Typically, the sealing material surmounting the plurality of channels is less than 500 nanometers thick, hi certain embodiments, the sealing material surmounting the plurality of channels can be less than: 100 nm, 50 nm, 25 nm, 10 nm, and 5 nm thick. Typically the sealing, material surmounting fee plurality- of channels is at least 1 nanometer thick, and snore typically at least 2 nm thick. In certain embodiments of the present invention, a step of removing a portion of the sealing material is used to reduce the thickness of the sealing material above at least one channel. Sealing material can be removed by a variety of etching and ebeam deposition methods as further described herein.

[0088] In another aspect of the present invention, there is provided a nanofludic chip that includes a nanochannel array of the present invention. Referring to FIG. 5 the nanofluidic chip 200 has a nanochannel array 100, a substrate 146, and reservoirs 144 for samples and waste (or sample collection). Further provided is FIG. 5 are auxiliary sample ports 140 and auxiliary waste ports for handling fluid sample. The reservoirs are in fluid communication with at least one of the channels, so that the sample reservoirs are capable of releasing a fluid into the channels, and the waste reservoirs are capable of receiving a fluid from the channels. Typically the fluids contain macromolecules for analysis.

[0089] In certain embodiments of the present invention, the nanofludic chip contains at least one sample reservoir is formed in the surface of the substrate. Steps to form reservoirs in nanochannel array substrates are provided above. In this embodiment, at least one waste reservoir in fluid communication with at least one of the channels. Typically, the nanofluidic chip contains at least 1 sample reservoir. A variety of other embodiments include at least 96 reservoirs, and even at least 1000 reservoirs in the nanofluidic chip.

[0090] For use in macromolecular analysis, it is preferred that the nanofludic chip provides at least a portion, of the nanochannel array capable of being imaged with a two-dimensional detector. Imaging of the array is provided by presenting the scaling material face of the nanochannel array to suitable apparatus for the collection of emitted signals, such as optical elements for the collection of light from the nanochannel array. In this embodiment, the nanofluidic chip is capable of transporting a plurality of elongated macromolecules from a sample reservoir and across the channels.

[0091] Is certain embodiments of the present invention, the nanofluidic chip contains an apparatus for transporting macromolecules from the sample reservoirs, through the channels, and into the waste reservoirs. A suitable apparatus includes at least one pair of electrodes capable of applying an electric field across at least some of the channels in at least one direction. Electrode metal contacts can be integrated using standard integrated circuit fabrication technology to be in contact with at least one sample and at least one collection/waste reservoir to establish directional electric field. Alternating current (AC), direct current (DC), or both types of fields can be applied. The electrodes can be made of almost any metal, and are typically thin Al/Au metal layers deposited on defined line paths. Typically at least one end of one electrode is in contact with buffer solution in the reservoir.

[0092] In certain embodiments of the present invention, the nanofluidic chip contains at least two pair of electrodes, each providing an electric field in different directions. In this embodiment, adjacent clusters of channels connect individual isolated reservoir. With at least two sets of independent electrodes, field contacts can be used to independently modulate the direction and amplitudes of the electric fields to move macromolecules at desired speed or directions.

[0093] In another aspect of the present invention, there is provided a system (FIG. 10, 300) that is suitable for carrying out macromolecular analysis. In the present invention, the system includes a nanofluidic chip as described herein, and an apparatus for detecting at least one signal transmitted from one or more fluids in the nanochannel array of the nanofludic chip.

[0094] In various embodiments of the present invention, the system further includes at least one of the following: a transporting apparatus to transport a fluid through at least one of the channels; a sample loading apparatus for loading at least one fluid to the sample reservoirs in the nanofludic chip; and a data processor. The various components of the system 300 are connected together, and the general principles of operation are illustrated in FIG. 10.

[0095] The nanofludic chip 300 used in the system is typically disposable, individually packaged, and having a sample loading capacity of 1-50,000 individual fluid samples. The nanofluidic chip typically has at least one interconnecting sample delivery microchannel to provide fluid samples into the channels, as well as sample loading openings and a reservoir, or sample loading openings and plates connected with a sealing mechanism, such as an O-ring. Metal contacts for connecting the electrodes 292 and an electric potential generator 216 are also provided in the nanofluidic chips. Suitable metal contacts can be external contact patches that can be connected to an external scanning/imaging/electric-field tuner.

[0096] The nanofluidic chip is preferably encased in a suitable housing, such as plastic, to provide a convenient and commercially-ready cartridge or cassette. Typically the nanofluidic cartridges will have suitable features on or in the housing for inserting, guiding, and aligning the sample leading device with the reservoirs. Insertion slots, tracks, or both can be provided in the plastic case.

[0097] Macromolecular fluid samples that can be analyzed by the system includes fluids from a mammal, (e.g., DMA, cells, blood, biopsy tissues), synthetic macromolecules such as polymers, and materials found in nature (e.g., materials derived from plants, animals, and other life forms). Such said samples can be managed, loaded, and injected using automated or manual sample loading apparatus of the present invention.

[0098] In one embodiment of the present invention, the system includes an apparatus to excite the macromolecules inside the channels and detect and collect the resulting signals. A suitable apparatus is illustrated in FIG. 10; a laser beam 204 is focused using a focusing lens 206 to a spot on the nanochannel array 100. The generated light signal from the macromolecules inside the channels (not shown) is collected by a collection lens 208, and reflected off a dichroic mirror 218 into an optical path 220, which is fed into a CCD (charge coupled device) camera. Various optical components and devices can also be used in the system to detect optical signals, such as digital cameras, PMTs (photomultlplier tubes), and APDs (Avalanche photodiodes.

[0099] In another embodiment of the present invention, the system includes a data processor. The data processor can be used to process the signals from the CCD to project the digital image of the nanochannel array on a display 212. The data processor can also analyze the digital image to provide characterization information, such as macromolecular size statistics, histograms, karyotypes, mapping, diagnostics information and display the information in suitable form for data readout 214.

[0100] In another aspect of the present invention, there is provided a method of analyzing at least one macromolecule. In this invention, the analysis includes the steps of providing a nanofluidic chip according to the present invention, providing the at least one sample reservoir with at least one fluid, said fluid comprising at least one macromolecule; transporting the at least one macromolecule into the at least one channel to elongate said at least one macromolecule; detecting at least, one signal transmitted horn the at least one elongated macromolecule; and correlating the detected signal to at least one property of the at least one macromolecule.

[0101] In one embodiment of the present invention, the method of analyzing a macromolecule includes wetting the channels rising capillary action with a buffer solution or a buffer solution containing macromolecules. Macromolecules such as polymers and DNA can introduced into nanochannel arrays by electric field.

[0104] Macromolecule fluid samples can be loaded through reservoirs in the nanofluidics chip and transported via interconnecting microchannels. The macromolecules are partially elongated before one end of the macromolecule enters the channels; they are substantially fully elongated when completely inside the channels. The fluorescent signals can be excited by the appropriate excitation sources and emission signals can be collected via imaging camera or detectors, in a linear scanning mode or CCD image integration. The signals collected can be analyzed by data processing software and user-defined major parameters (intensity/photons, major axis, minor axis, background signal)can be recorded and measured.

[0106] The typical concentration of the macromolecules in the fluid will be one macromolecule, or about at least attogram per ml, more typically at least one femtogram per ml, more typically at least one picogram per ml, and even more typically at least one nanogram per ml. Concentrations will typically be less than 5 micrograms per milliliter and more typically less than 0.5 micrograms per milliliter.

[0111] After NIL and etching, non-uniform deposition of sealing material was provided by e-beam evaporation with a tilted sample wafer at various angles or sputter deposition using a large source target. This step was used to both reduce the trench width and seal the channels.

[0113] In the following examples, nanochannel arrays were prepared using a process to deposit SiO.sub.2 sealing material, on patterned substrates by sputtering. Channel openings were prepared, by cleaving the substrate and imaged by Scanning Electronic Microscope (SEM). Results are as follows and shows mat the trench widths are narrowed by the deposition of the sealing material using sputtering:

Example 1

[0114] A 100 mm silicon substrate was provided having a plurality of parallel linear channels that had an 85 nm trench width and a 200 nm trench height (FIG. 7a). This substrate was sputtered at a gas pressure of 5 mTorr according to the general procedures given above. After sputtering, the channels had a 52 nm trench width, a 186 nm, trench height, and a seal thickness of 200 nm (FIG. 7b). Apparently, the trench height increased slightly as a result of the sealing process forming a cone-shaped seal shove the channel.

Example 2

[0115] A patterned substrate having a 65 nm trench width and about 100 nm trench height prior to sputtering formed a nanochannel array having a 17 nm trench width, a 68 nm bench height, and a channel seal thickness of about 350 nm. Sputtering gas pressure was 5 mTorr.

Example 3

[0116] A patterned substrate having a 50 nm trench width and about 80 nm trench depth prior to spattering formed a nanochannel array having a 10 nm trench width, 51 nm trench height, and a channel seal thickness of 350 nm. Sputtering gas pressure was 5 mTorr.

Example 4

[0117] A substrate containing a two-dimensional array of pillars was made using a two-step NIL process with the channel amid rotated 90.degree. between the imprinting steps (FIG. 6a). The pillar array structure, is subsequently completely sealed with silicon dioxide using a 29 minute deposition time. The seal thickness was about 500 nm. A profile view of the channel is depleted in FIG. 6b and a top view of the completely sealed nanochannel array is depicted in FIG. 6d.

Example 5

[0118] Example 4 was repeated except the sputter deposition time was 17 minutes to provide a nanochannel array that is not completely sealed. A top view scanning electron micrograph of this nanochannel array is provided In FIG. 6d. The seal thickness was 300 nm.

Example 6

[0119] A nanoslit is provided in a channel prepared with a silicon dioxide sealing material for carrying out near-field analysis saving a seal thickness greater than about 100 nm is modified by using FIB to create a nanoslit having a thicknessless than 100 nm. FIG. 8 shows a schematic of how the deposited sealing material on a nanochannel array is first milled away using FIB from the sealing material situated above the sealed channels. Subsequently, aluminum is deposited to create an opaque layer to provide optical contrast at the slit.

Example 7

[0120] This example shows bow a nanochannel array can be prepared from a substrate having a plurality channels larger than 150 nm wide by 150 nm deep. A substrate is prepared by photolithography techniques to provide a plurality of channels with width of greater than 1.5 micron using conventional optical lithography techniques. Contact aligner such as Karl Suss MA-6 to provide a pattern resolution at low micron level; Industrial projection stepper. The angle of the incident depositing beam of sealing material is varied to reduce the trench width and height to less than 150 nm and 150 nm, respectively, and to substantially seal by providing shallow tangential deposition angles.

Example 8

[0121] This example provides a nanochannel array using an e-beam, technique. A substrate is provided, as in Example 1. Silicon dioxide is deposited by an e-beam (thermo) evaporator (Temescal BJD-1800) onto the substrate. The substrate is placed at various angles incident to the depositing beam from the silicon dioxide source target; the deposition rate is set to about 3 nm/minute and 150 nm of sealing material is deposited in about 50 minutes.

Example 9

[0122] In this example, a nanochannel array is contacted with a surface-modifying agent. A nanochannel array made according to Example 1 is submerged in a surface-modifying agents solutions containing polyethylene glycol inside a vacuum chamber overnight to facilitate wetting and treatment of the channels and degas the air bubbles that might be trapped inside the channels.

Example 10

[0123] This example shows the preparation of a nanochannel array having a metal sealing material. An e-beam (thermo) evaporator (Temescal BJD-1800) was used to deposit Chromium (Cr) onto a nanochannel array chip (trench width 80 nm, trench depth 80 nm, SiO2/Si substrate). The substrate was placed at various angles to the incident depositing beam from the source target, the deposition rate was set at 2.0-3.6 nm/minute. The resulting trench width was 20 nm, trench depth less than 80 nm, and the channels were substantially closed.

Example 11

[0124] This example shows the process of adding an optically opaque layer to a nanochannel array. A nanochannel array made according to Example 3 is placed perpendicular to the incident depositing beam, to provide an opaque layer less than 50 nm thick. An aluminum source target is selected for depositing on top of the SiO2 sealing material above the sealed channels. The deposition rate was set at 2.0-3.6 nm/minute.

Example 12

[0125] This example describes the steps needed to provide a near-field slit in a nanochannel array. FIB was used to mill narrow silts less than 50 nm in width in the direction, perpendicular to the long axis of the nanochannel array of Example 11. The depth of the FIB milling was controlled to expose the underlying thin SiO2 sealing material above the nanochannel array.

Example 13

[0126] This example describes how to provide a sample reservoir with a nanochannel array to provide a nanofludic chip. A nanochannel array having 100 nm wide, 100 nm deep channels was made according to general procedures of Example 1. The nanochannel array was spin-coated with a photoresist and imaged with a photomask, to provide regions on opposite ends of the nanochannel array. The exposed areas were etched using reactive ion etching to expose the channel ends and to provide a micron-deep, reservoir about a millimeter wide on the opposite ends of the channels at the edge of the substrate.

Example 14

[0127] This example describes how to fill a nanofluidic chip with a fluid containing DNA macromolecules to analyze the DNA. A cylindrical-shaped plastic sample-delivery tube of 2 mm diameter was placed in fluid communication with one of the reservoirs of the nanochannel array of Example 13. The delivery tube is connected to an external sample delivery/collection device, which is in torn connected to a pressure/vacuum generating apparatus. The channels are wetted using capillary action with a buffer solution. A buffer solution containing stained lambda phage macromolecules (lambda DMA) were introduced into the nanochannel array by electric field (at 1-50 V/cm); the solution concentration was 5 microgram/mL and the lambda DMA was stained at a ratio of 10:1 base pair/dye with the dye TOTO-1 (Molecular Probes, Eugene, Org.). This solution of stained DNA was diluted to 0.1-0.5 microgram/mL into 0.5.times.TBE (tris-boroacetate buffer at pH 7.0) containing 0.1M of an anti-oxidant and 0.1% of a linear polyacrylamide used as an anti-sticking agent.

Example 14

[0128] A nanofluidic chip made according to Example 12, having channel dimensions of 100 nm.times.100 nm was filled using capillary action with a buffer solution containing stained genomic DNA to draw the DNA macromolecules into the channels with an electric field. Bacteria phage DNA molecules Lambda (48.5 kb) and T4 (168.9 kb) were stained with the dye TOTO-1 and BOBO-3 respectively. This solution of stained DNA was diluted to 0.5 .mu.g/mL into 0.5 .times. TBE containing 0.1 M dithlothreatol as an anti-oxidant and 0.1% of a linear acrylamide used as an anti-sticking agent). A Nikon Eclipse TE-300 inverted microscope with a 60.times. (N.A. 1.4) oil immersion objective was used with an Ar:K laser (Coherent Lasers) as an excitation source at 488 nm and 570 nm. A Roper Scientific Peotamax intensified cooled CCD camera with a 512.times.512 pixel array and 16 bits digital output-was used to image the molecules. Digital Image was analyzed using a data processor by NTH Image software. FIG. 9b shows an integrated image of the stretched Lambda and T4 phage genomes side by side in the channels. The inset of 9b shows the near perfect linear fit of the directly measured length obtained from the digital image plotted against their genome size, (R2 is 0.99996). FIG. 9c shows an army of fluorescently-labled genomic DNA molecules aligned and stretched in the channels with the size ranging from 10 kb to 194 kb. This shows that millions of center-meter long parallel channels could be fabricated over the whole wafer. Accordingly, the entire length of genomic DNA molecules can be stretched and analyzed.

Example 15

[0129] Example 14 is repeated, but with a 96 multiple reservoir system. A nanofludic chip made according to Example 12 is modified with a photomask to provide 96 sample reservoirs, each reservoir connected to 1000 channels along one edge of the 100 mm substrate. 96 different DMA samples are delivered and injected using capillary fibers connected to the sample reservoirs. 96 collection reservoirs are connected to the corresponding ends of the channels to collect the DNA samples.

Example 16

[0130] This example describes a system used for carrying out analysis of macromolecules. The system contains an automated 96-caplilary auto-injection sample loader to deliver 96 macromolecular fluid samples into the delivery ports of a nanofluidic cartridge. The nanofluidic cartridge is a nanofluidic chip encased by a plastic polycarbonate housing, having delivery ports and collection ports for connection to microcapillary tubing, and embedded metal contacts for connection to electrodes on the nanofluidic chip. The cartridge can be inserted in a cartridge holder, which is integrated with an a laser excitation source and suitable optical components to provide the excitation of and collection of optical signals emanating from sample fluids within the nanochannel arrays of the nanofluidic chip. The signal detection/collection apparatus is a cooled CCD digital camera. Signals from the digital camera are analyzed by a data processor using NIH image analysis software, and displayed on a monitor.

Example 17

[0131] This example describes how to use the system of Example 16 to size one DNA macromolecule. A single Anthrax spore is lysed to extract its entire genomic contents (DNA) with 10 microliters of a buffer solution and stained with fluorescent dyes. The sample loader is inserted into the delivery ports of the cartridge and injects the DNA-containing fluid. The electrodes are activated and the DNA macromolecules are transported into the nanochannel array, where they become elongated. The fluorescent steins on die DMA are excited by the excitation source, and their emission signals are collected using the CCD cameras. The signals collected, analyzed and recorded for intensity and position by the data processor. The length of a single DMA is detected and intensity profile is plotted.

[0132] In another aspect of the present invention, there is provided 144. A cartridge comprising at least one nanofluidic chip, said cartridge capable of being inserted and removed from a system for carrying out macromolecular analysis, said at least one nanofluidic chip comprising at least one nanonanochannel array, said nanonanochannel array comprising.

[0133] a surface having a plurality of channels in the material of the surface, said channels having a trench width of less than about 150 nanometers and a trench depth of less than 200 nanometers;

[0134] at least some of the channels being surmounted by sealing material to render such channels at least substantially enclosed.

Wicking Mob – Unleashing Flawed Patents by USPTO

Cruel Reality – Lawyers are messing with science on intellectual property affairs as they have no handle on it.

So, collusion with USPTO is unleashing a wave of flawed patents like this one more below:

Scientific Flaw.

The ‘wick’ 34 cannot work below the water table reference.

The device 34 is just a porous drain and never a wick.

Wick is a device on oil lamps that takes fuel toward the flame inside the Unsaturated Hydraulic Zone (Negative Pressure).

Lay people employing wicking terminology does not understand oil lamps and the functioning of wicks.

My Demand to USPTO

It is not that hard to argue at the Court of the Law that Hydrological issues should be examined by Hydrologists.

My demand to USPTO is the same as the first letter sent on Oct. 2006:

1. Hire Examiners with background in Hydrogeology and/or Soil Physics so that they have full comprehension of fluids moving on porosity;

2. Cancel issued patents with scientific flaws. Obsolete patents are cancelled naturally by becoming outdated;

3. Make a public statement about Hydrology negligence hurting all Hydrological community as well as my project that needs experts in Hydrology to protect the content of my issued claims.

4. Compensate for my losses since as an inventor filing patents I was not expecting lay people handling hydrology in the examination process by USPTO.

5. Since USPTO is failing to protect my IP rights my patents should be eligible for time extension of their expiration dates (new demand).

6. Issue a bill requiring Hydrology be handled by Hydrologists preventing laypeople from harming standing common knowledge in the scientific literature (new demand).

7. Make people accountable for breaking the Law regarding my complaints (new demand).

_______________________________________________________________________________

Understanding the bias – The size of the Hydrological Gap

Wick/wicking is not a word found on my Hydrology textbooks but it is in the patent classification system at USPTO guiding lay inventors and lay Patent Examiners pretending they are known in the art.

In 1856 Henry Darcy proposed an equation Law to address fluids moving on porosity for Hydraulic Conductivity. Afterwards in 1907 Edward Buckingham suggested a change to address negative pressure flow for Unsaturated Hydraulic Flow (wick/wicking).

Today May 12, 2014 searching at USPTO:

Thermal/Heat Conductivity is mentioned in 96,025 issued patents

Electrical/Electric Conductivity is mentioned in 72,719 issued patents

Saturated Hydraulic Conductivity mentioned in only 702 issued patents

Hydraulic Conductivity (wicking for lay people) is mentioned in only 27 issued patents

Wick/wicking (Unsaturated Flow if not flawed) is mentioned in 32,206 issued patents

_______________________________________________________________________________

Abraham Duncan Stroock

Dept: Chemical and Biomolecular Engineering

Title: Associate Professor

email: ads10@cornell.edu

Education

Ph.D., Harvard University, Chemical Physic (2002)

M.S., University Paris VI and XI,Solid State Physics (1997)

B.A. Cornell University, Physics (1995)

De: Abraham Duncan Stroock [mailto:abe.stroock@cornell.edu]

Enviada em: terça-feira, 22 de abril de 2014 22:20
Para: Elson Silva, PhD

Assunto: RE: [06856] Protecting Hydrology Science from REINVENTION by corrupt LAY PEOPLE colluding with USPTO - US Pat 8,701,469

Dear Dr. Silva,

‘... If you have a point to make about my treatment of hydrological concepts, I ask that you take the time to explain your specific points of disagreement. I note that my work is better represented in my publications (available at http://www.stroockgroup.org/home/publications) than in patents, as the lawyers have been translated the latter into legalese that I do not understand.’

Best regards,

Abe

___________________________________________________________

De: Elson Silva, PhD [mailto:el_silva@uol.com.br]
Enviada em: terça-feira, 22 de abril de 2014 23:40
Para: 'Abraham Duncan Stroock'
Cc: cko3@cornell.edu; TDO1@cornell.edu; MGS22@cornell.edu; SBW11@cornell.edu; el_silva@uol.com.br
Assunto: RES: [06856] Protecting Hydrology Science from REINVENTION by corrupt LAY PEOPLE colluding with USPTO - US Pat 8,701,469

Prioridade: Alta

Abe,

You are so naive.

‘…Are you sure you got your PhD at Harvard? ‘

Lawyers learn nothing about Hydrology in Law School.

As far as I know no Law School provides Hydrology teaching . . . No Lawyer could discuss Hydrology having no expertise in the subject!

This is funny!

You do not give your scientific papers to Lawyers, so why are your patents different?

(By the way, was it a Lawyer who wrote your PhD thesis?)

Also, Lawyers are illiterate on the functioning of science, besides most scientists have no idea about Epistemology, Metaphysics, Logics, and History of Science (Philosophy of Science).

USPTO is a sham system allowing reinvention sometimes by flawed lazy patents from wealthy parties letting Lawyers step over boundaries beyond their background in Law Schools….’

I would like to invite people around the world to send messages to those 14,302 emails below pledging them to be honest and stop violating intellectual property rights allowing huge corporations and UNIVERSITIES to reinvent issued patents shamefully dishonoring HYDROLOGY SCIENCE and breaking the Law.

0756353@princeton.edu

a_a_a@princeton.edu

aa2pupp@princeton.edu

aa4@princeton.edu

aaakhtar@princeton.edu

aabdill@princeton.edu

aabend@princeton.edu

aacciava@princeton.edu

aache@princeton.edu

aacheng@princeton.edu

aacs@princeton.edu

aad3@princeton.edu

aadcroft@princeton.edu

aades@princeton.edu

aaen@princeton.edu

aaf2@princeton.edu

aaftab@princeton.edu

aahouck@princeton.edu

aajalota@princeton.edu

aakhtar@princeton.edu

aakiho@princeton.edu

aalcanta@princeton.edu

aalkhate@princeton.edu

aam4@princeton.edu

aambrose@princeton.edu

aambrosi@princeton.edu

aamgalan@princeton.edu

aamirz@princeton.edu

aamwake@princeton.edu

aanab@princeton.edu

aandres@princeton.edu

aanghel@princeton.edu

aanlas@princeton.edu

aanuzis@princeton.edu

aapotts@princeton.edu

aarcamon@princeton.edu

aaronag@princeton.edu

aaronbs@princeton.edu

aaroncr@princeton.edu

aaronmb@princeton.edu

aaronml@princeton.edu

aaronms@princeton.edu

aaronv@princeton.edu

aarsleff@princeton.edu

aarya@princeton.edu

aashok@princeton.edu

aasil@princeton.edu

aatishb@princeton.edu

aaurich@princeton.edu

aav5@princeton.edu

aave@princeton.edu

aayako@princeton.edu

aayala@princeton.edu

ab14@princeton.edu

ab18@princeton.edu

ab23@princeton.edu

abachas@princeton.edu

abadura@princeton.edu

abahat@princeton.edu

abalaji@princeton.edu

abalistr@princeton.edu

aballing@princeton.edu

abanful@princeton.edu

abaruzzi@princeton.edu

abarysh@princeton.edu

abasak@princeton.edu

abazadze@princeton.edu

abbym@princeton.edu

abd@princeton.edu

abd2@princeton.edu

abdiels@princeton.edu

abeatty@princeton.edu

abeck@princeton.edu

abelarmi@princeton.edu

abenhaim@princeton.edu

aberdahl@princeton.edu

aberven@princeton.edu

abharris@princeton.edu

abhig@princeton.edu

abhimanyu.shah@princeton.edu

abi@princeton.edu

abigailf@princeton.edu

abigailj@princeton.edu

abigaill@princeton.edu

abigailr@princeton.edu

abilal@princeton.edu

abingham@princeton.edu

abland@princeton.edu

ablankst@princeton.edu

ableach@princeton.edu

abm@princeton.edu

abmiller@princeton.edu

aboden@princeton.edu

abogdan@princeton.edu

abollfra@princeton.edu

abolton@princeton.edu

aboltz@princeton.edu

aboost@princeton.edu

aboote@princeton.edu

aboozer@princeton.edu

aborders@princeton.edu

aborkar@princeton.edu

aborovoy@princeton.edu

aboyko@princeton.edu

abragg@princeton.edu

abrahamb@princeton.edu

abraitis@princeton.edu

abrarc@princeton.edu

abrewer@princeton.edu

abruno@princeton.edu

abruzos@princeton.edu

abryant@princeton.edu

abtorres@princeton.edu

abucher@princeton.edu

abuchner@princeton.edu

abuddhir@princeton.edu

aburbach@princeton.edu

aburns@princeton.edu

aburrows@princeton.edu

abursak@princeton.edu

abustin@princeton.edu

abuzgo@princeton.edu

abw@princeton.edu

abyrnes@princeton.edu

ac13@princeton.edu

ac17@princeton.edu

ac18@princeton.edu

ac19@princeton.edu

ac2@princeton.edu

acalcado@princeton.edu

acampion@princeton.edu

acantore@princeton.edu

acapacci@princeton.edu

acapece@princeton.edu

acapers@princeton.edu

acaputo@princeton.edu

acarmstr@princeton.edu

acarpe@princeton.edu

acarson@princeton.edu

acaswell@princeton.edu

acatena@princeton.edu

acb@cs.princeton.edu

acbank@princeton.edu

accase@princeton.edu

accohen@princeton.edu

acelia@princeton.edu

acerf@princeton.edu

acevedo@princeton.edu

acham@princeton.edu

achan@princeton.edu

achaney@princeton.edu

achang@princeton.edu

achase@princeton.edu

achauhan@princeton.edu

achavda@princeton.edu

achebet@princeton.edu

achen@princeton.edu

acheong@princeton.edu

acherr@princeton.edu

achiarel@princeton.edu

achini@princeton.edu

achiraz@princeton.edu

achokshi@princeton.edu

achorti@princeton.edu

achoufri@princeton.edu

achpupp@princeton.edu

achriste@princeton.edu

achusan@princeton.edu

acifelli@princeton.edu

aclopez@princeton.edu

acm2@princeton.edu

acm4@princeton.edu

acofino@princeton.edu

acole@princeton.edu

acolson@princeton.edu

aconway@princeton.edu

acorina@princeton.edu

acorreia@princeton.edu

acorwin@princeton.edu

acostanz@princeton.edu

acostin@princeton.edu

acoyle@princeton.edu

acraft@princeton.edu

acrager@princeton.edu

acraiutu@princeton.edu

acraven@princeton.edu

acreely@princeton.edu

across@princeton.edu

acruser@princeton.edu

acruz@princeton.edu

acuba@princeton.edu

acupid@princeton.edu

acurevac@princeton.edu

acutchin@princeton.edu

acwilk@princeton.edu

acyue@princeton.edu

aczulak@princeton.edu

ad11@princeton.edu

ad12@princeton.edu

ad7@princeton.edu

ad8@princeton.edu

ad9@princeton.edu

adadamo@princeton.edu

adadas@princeton.edu

adahmed@princeton.edu

adamc@princeton.edu

adamdk@princeton.edu

adamdw@princeton.edu

adame@princeton.edu

adamico@princeton.edu

adamjl@princeton.edu

adamjs@princeton.edu

adamre@princeton.edu

adamsm@princeton.edu

adamwolf@princeton.edu

adamz@princeton.edu

adasilva@princeton.edu

adbaker@princeton.edu

ade2@princeton.edu

adebutts@princeton.edu

adegenna@princeton.edu

adegnan@princeton.edu

adel@princeton.edu

adelaide@princeton.edu

adele@princeton.edu

adelman@princeton.edu

ademetri@princeton.edu

adeng@princeton.edu

adesio@princeton.edu

adettwil@princeton.edu

adewunmi@princeton.edu

adezubay@princeton.edu

adhauptm@princeton.edu

adhikari@princeton.edu

adhillon@princeton.edu

adho@princeton.edu

adhughes@princeton.edu

adiaz@princeton.edu

adif@princeton.edu

adina@princeton.edu

adinescu@princeton.edu

adinw@princeton.edu

adioses@princeton.edu

adler@ias.edu

admullen@princeton.edu

adnewman@princeton.edu

adogariu@princeton.edu

adolfsen@princeton.edu

adoll@princeton.edu

adong@princeton.edu

adonsky@princeton.edu

adopupp@princeton.edu

adr2@princeton.edu

adrianav@princeton.edu

adrianna@princeton.edu

adriant@princeton.edu

adrosa@princeton.edu

adsera@princeton.edu

adsingh@princeton.edu

adsmith@princeton.edu

adsouza@princeton.edu

adstanle@princeton.edu

adube@princeton.edu

aduca@princeton.edu

adudley@princeton.edu

advorkin@princeton.edu

ae3@princeton.edu

aeakes@princeton.edu

aeatkins@princeton.edu

aebennet@princeton.edu

aedantzl@princeton.edu

aefield@princeton.edu

aeherts@princeton.edu

aehiggin@princeton.edu

aej2@princeton.edu

aejinseo@princeton.edu

aelamb@princeton.edu

aelcano@princeton.edu

aeltvedt@princeton.edu

aemiller@princeton.edu

aemorton@princeton.edu

aemurray@princeton.edu

aene@princeton.edu

aensbury@princeton.edu

aesomers@princeton.edu

aestone@princeton.edu

aestrada@princeton.edu

aewagner@princeton.edu

af@cs.princeton.edu

af16@princeton.edu

afager@princeton.edu

afaiola@princeton.edu

afalcon@princeton.edu

afang@princeton.edu

afarman@princeton.edu

afaveri@princeton.edu

afbitbol@princeton.edu

afeia@princeton.edu

afelice@princeton.edu

afenley@princeton.edu

aferg@princeton.edu

aferraro@princeton.edu

aferris@princeton.edu

afisch@princeton.edu

afkarim@princeton.edu

afleming@princeton.edu

afmiller@princeton.edu

afogg@princeton.edu

aford@princeton.edu

aforden@princeton.edu

aforte@princeton.edu

afortgan@princeton.edu

afowler@princeton.edu

afraisse@princeton.edu

afrazier@princeton.edu

africano@princeton.edu

afrisby@princeton.edu

afshu@princeton.edu

afuente@princeton.edu

afulger@princeton.edu

afung@princeton.edu

afurger@princeton.edu

afyabrou@princeton.edu

ag13@princeton.edu

agabb@princeton.edu

agaffney@princeton.edu

agammie@princeton.edu

aganguly@princeton.edu

agans@princeton.edu

agarzon@princeton.edu

agataf@princeton.edu

agatlin@princeton.edu

agawu@princeton.edu

agaylord@princeton.edu

agbrown@princeton.edu

agdoyle@princeton.edu

ageana@princeton.edu

agease@princeton.edu

ageiger@princeton.edu

ageilker@princeton.edu

agellman@princeton.edu

agengos@princeton.edu

agersoff@princeton.edu

agetraer@princeton.edu

agewirtz@princeton.edu

aggrant@princeton.edu

aghoshal@princeton.edu

aghsieh@princeton.edu

agiovann@princeton.edu

agisaek@princeton.edu

agissing@princeton.edu

aglaser@princeton.edu

aglass@princeton.edu

aglidden@princeton.edu

agola@princeton.edu

agolden@princeton.edu

agoncalv@princeton.edu

agontijo@princeton.edu

agoodman@princeton.edu

agoretti@princeton.edu

agorrell@princeton.edu

agould@princeton.edu

agoun@princeton.edu

agoy@princeton.edu

agp2@princeton.edu

agpapa@princeton.edu

agpupp@princeton.edu

agrasso@princeton.edu

agraver@princeton.edu

agrigory@princeton.edu

agsmith@princeton.edu

aguijosa@princeton.edu

aguler@princeton.edu

agunarat@princeton.edu

agurel@princeton.edu

agwenger@princeton.edu

agyapong@princeton.edu

agyenis@princeton.edu

ah12@princeton.edu

ah13@princeton.edu

ah14@princeton.edu

ah2@princeton.edu

ah7@princeton.edu

ahackett@princeton.edu

ahadap@princeton.edu

ahady@princeton.edu

ahagan@princeton.edu

ahager@princeton.edu

ahajian@princeton.edu

ahalder@princeton.edu

ahamzawy@princeton.edu

ahaniogl@princeton.edu

ahanna@princeton.edu

ahardal@princeton.edu

aharjo@princeton.edu

ahartnet@princeton.edu

ahartz@princeton.edu

ahatcher@princeton.edu

ahberg@princeton.edu

ahcohen@princeton.edu

aheck@princeton.edu

ahelber@princeton.edu

ahepler@princeton.edu

ahepupp@princeton.edu

aherpupp@princeton.edu

ahickok@princeton.edu

ahl@princeton.edu

ahli@princeton.edu

ahmedh@princeton.edu

ahmet@tremor.princeton.edu

ahmin@princeton.edu

ahneman@princeton.edu

ahoffenb@princeton.edu

aholt@princeton.edu

ahondo@princeton.edu

ahopkins@princeton.edu

ahouse@princeton.edu

ahparikh@princeton.edu

aht@princeton.edu

ahua@princeton.edu

ahuckoo@princeton.edu

ahunter@princeton.edu

ahupbach@princeton.edu

ahwu@princeton.edu

ahxu@princeton.edu

ahzhou@princeton.edu

aianni@princeton.edu

aih2@princeton.edu

aimeea@princeton.edu

aimmel@princeton.edu

aimmerwa@princeton.edu

ainecik@princeton.edu

ainnocen@princeton.edu

ainslie@princeton.edu

aionescu@princeton.edu

airiza@princeton.edu

aishan@princeton.edu

aisun@princeton.edu

aitor@princeton.edu

aitzkowi@princeton.edu

aivanov@princeton.edu

aiwalker@princeton.edu

aizenman@princeton.edu

ajacques@princeton.edu

ajafari@princeton.edu

ajah@princeton.edu

ajalvare@princeton.edu

ajamal@princeton.edu

ajavadia@princeton.edu

ajavitt@princeton.edu

ajayakum@princeton.edu

ajc2@princeton.edu

ajcashel@princeton.edu

ajcj@princeton.edu

ajcollin@princeton.edu

ajday@princeton.edu

ajdechet@princeton.edu

ajdixon@princeton.edu

ajeannette@princeton.edu

ajeon@princeton.edu

ajgottli@princeton.edu

aji@princeton.edu

ajiao@princeton.edu

ajjones@princeton.edu

ajkatz@princeton.edu

ajlink@princeton.edu

ajoo@princeton.edu

ajost@princeton.edu

ajow@princeton.edu

ajpayne@princeton.edu

ajpowell@princeton.edu

ajrodger@princeton.edu

ajs5@princeton.edu

ajs6@princeton.edu

ajs7@princeton.edu

ajsb@princeton.edu

ajschmid@princeton.edu

ajtrosko@princeton.edu

ajudge@princeton.edu

ajuliano@princeton.edu

ajunn@princeton.edu

ajw2@princeton.edu

ajwong@princeton.edu

ajy@princeton.edu

ak11@princeton.edu

ak12@princeton.edu

ak13@princeton.edu

ak15@princeton.edu

ak17@princeton.edu

aka@princeton.edu

akachuck@princeton.edu

akalett@princeton.edu

akalwa@princeton.edu

akao@princeton.edu

akarels@princeton.edu

akarki@princeton.edu

akasdin@princeton.edu

akashj@princeton.edu

akashl@princeton.edu

akashs@princeton.edu

akassam@princeton.edu

akattis@princeton.edu

akawal@princeton.edu

akaye@princeton.edu

akd@princeton.edu

akenrick@princeton.edu

akernan@princeton.edu

akersley@princeton.edu

akerwick@princeton.edu

akessell@princeton.edu

akesselm@princeton.edu

akfour@princeton.edu

akg@princeton.edu

akgee@princeton.edu

akgonzal@princeton.edu

akhanna@princeton.edu

akhild@princeton.edu

akhodak@princeton.edu

akhoshno@princeton.edu

akielar@princeton.edu

akildare@princeton.edu

akilian@princeton.edu

akimbrou@princeton.edu

akjackso@princeton.edu

akkerman@princeton.edu

akl2@princeton.edu

aklosowi@princeton.edu

akloth@princeton.edu

aklutey@princeton.edu

akm3@princeton.edu

akmccall@princeton.edu

akmehra@princeton.edu

akmin@princeton.edu

akneel@princeton.edu

aknox@princeton.edu

akocar@princeton.edu

akonca@princeton.edu

akoo@princeton.edu

akopec@princeton.edu

akorenny@princeton.edu

akr@princeton.edu

akratzer@princeton.edu

akropp@princeton.edu

akrueger@princeton.edu

akruk@princeton.edu

aksarkar@princeton.edu

aksen@princeton.edu

akuaa@princeton.edu

akubiak@princeton.edu

akulier@princeton.edu

akurosu@princeton.edu

akusaka@princeton.edu

akustov@princeton.edu

akwagner@princeton.edu

akwillia@princeton.edu

akwong@princeton.edu

al@princeton.edu

al10@princeton.edu

al11@princeton.edu

al12@princeton.edu

al15@princeton.edu

al16@princeton.edu

al7@princeton.edu

al9@princeton.edu

alackey@princeton.edu

aladd@princeton.edu

alaing@princeton.edu

alaink@princeton.edu

alam@princeton.edu

alamb@princeton.edu

alanac@princeton.edu

alandes@princeton.edu

alangan@princeton.edu

alangdon@princeton.edu

alankrit@princeton.edu

alapite@princeton.edu

alargent@princeton.edu

alavrov@princeton.edu

alawson@princeton.edu

albanell@princeton.edu

albarran@princeton.edu

albertl@princeton.edu

albertr@princeton.edu

alda@princeton.edu

alecb@princeton.edu

aleciam@princeton.edu

aleeuwen@princeton.edu

aleiggi@princeton.edu

aleirios@princeton.edu

alemmer@princeton.edu

alessand@princeton.edu

alevine@princeton.edu

alewien@princeton.edu

alex.gottlieb@princeton.edu

alexd@princeton.edu

alexeeva@princeton.edu

alexh@princeton.edu

alexiah@princeton.edu

alexiak@princeton.edu

alexisds@princeton.edu

alexisr@princeton.edu

alexsokolov@princeton.edu

alezal@princeton.edu

alf@princeton.edu

alfenley@princeton.edu

alfredb@princeton.edu

alfredo@princeton.edu

alfredog@princeton.edu

alfredot@princeton.edu

algraham@princeton.edu

alherrer@princeton.edu

aliali@princeton.edu

aliauw@princeton.edu

alibby@princeton.edu

alicei@princeton.edu

alicem@princeton.edu

alicemp@princeton.edu

alicez@princeton.edu

alicialc@princeton.edu

alicini@princeton.edu

alicook@princeton.edu

aliisal@princeton.edu

alips@princeton.edu

alirezaf@princeton.edu

alissanu@princeton.edu

aliyag@princeton.edu

alizay@princeton.edu

aljackso@princeton.edu

alkelley@princeton.edu

allais@princeton.edu

allannad@princeton.edu

allerner@princeton.edu

alliang@princeton.edu

allisonb@princeton.edu

allisone@princeton.edu

allisonh@princeton.edu

alliston@princeton.edu

allyson@princeton.edu

allysonk@princeton.edu

almag@princeton.edu

almpupp@princeton.edu

alomip@princeton.edu

alomon@princeton.edu

aloo@princeton.edu

alotito@princeton.edu

alouie@princeton.edu

alouthan@princeton.edu

alovett@princeton.edu

alowman@princeton.edu

alrubins@princeton.edu

alsdorf@princeton.edu

alt2@princeton.edu

alta@princeton.edu

altabet@princeton.edu

altj@princeton.edu

altosaar@princeton.edu

alud@princeton.edu

aludomir@princeton.edu

aluijend@princeton.edu

alundin@princeton.edu

alunt@princeton.edu

alvan@princeton.edu

alvind@princeton.edu

alwr@princeton.edu

alysonb@princeton.edu

alyssal@princeton.edu

alyssam@princeton.edu

alyssap@princeton.edu

alzaibak@princeton.edu

alzp@princeton.edu

am2@princeton.edu

am24@princeton.edu

am26@princeton.edu

amacrae@princeton.edu

amadrid@princeton.edu

amaggi@princeton.edu

amah@princeton.edu

amahmoud@princeton.edu

amailyan@princeton.edu

amainzer@princeton.edu

amairone@princeton.edu

amaleh@princeton.edu

amalleo@princeton.edu

amalyam@princeton.edu

amamenis@princeton.edu

amamone@princeton.edu

amanda@princeton.edu

amandao@princeton.edu

amandres@princeton.edu

amanion@princeton.edu

amann@princeton.edu

amanoj@princeton.edu

amansuri@princeton.edu

amante@princeton.edu

amark@princeton.edu

amarkham@princeton.edu

amarquez@princeton.edu

amartill@princeton.edu

amas@princeton.edu

amassry@princeton.edu

amaul@princeton.edu

amayorga@princeton.edu

amazur@princeton.edu

amazzari@princeton.edu

ambartle@princeton.edu

amberlee@princeton.edu

ambikav@princeton.edu

amchen@princeton.edu

amcole@princeton.edu

amcpupp@princeton.edu

amdonova@princeton.edu

ame@princeton.edu

amegill@princeton.edu

amehmood@princeton.edu

ameirowi@princeton.edu

amelick@princeton.edu

amelloni@princeton.edu

amene@princeton.edu

ameng@princeton.edu

amensah@princeton.edu

amerle@princeton.edu

amerzhev@princeton.edu

ametts@princeton.edu

amfour@princeton.edu

amgeller@princeton.edu

amgreen@princeton.edu

amho@princeton.edu

amiksis@princeton.edu

amillar@princeton.edu

amimran@princeton.edu

amirr@princeton.edu

amissak@princeton.edu

amitava@princeton.edu

amits@princeton.edu

amjohnso@princeton.edu

amkelly@princeton.edu

amlerner@princeton.edu

amlombar@princeton.edu

amm@princeton.edu

amm6@princeton.edu

ammada@princeton.edu

ammar@princeton.edu

ammills@princeton.edu

amolnar@princeton.edu

amomenee@princeton.edu

amonach@princeton.edu

amonache@princeton.edu

amoores@princeton.edu

amora@princeton.edu

amoravcs@princeton.edu

amorgado@princeton.edu

amorozov@princeton.edu

amorreal@princeton.edu

amosova@princeton.edu

amoten@princeton.edu

amr7@princeton.edu

ams6@princeton.edu

amscott@princeton.edu

amsgro@princeton.edu

amtoth@princeton.edu

amurphy@princeton.edu

amusacch@princeton.edu

amusse@princeton.edu

amutschl@princeton.edu

amy.liu@princeton.edu

amy.mercogliano@princeton.edu

amyc@princeton.edu

amycar@princeton.edu

amydim@princeton.edu

amyh@princeton.edu

amyham@princeton.edu

amyhwang@princeton.edu

amylewis@princeton.edu

amynash@princeton.edu

amyoung@princeton.edu

amytai@princeton.edu

amywu@princeton.edu

an.repouliou@princeton.edu

an4@princeton.edu

an6@princeton.edu

anaddo@princeton.edu

anagy@princeton.edu

anaidu@princeton.edu

anandm@princeton.edu

ananduri@princeton.edu

anastase@princeton.edu

anastasy@princeton.edu

anatoly@princeton.edu

anavarro@princeton.edu

anb2@princeton.edu

anchondo@princeton.edu

andai@princeton.edu

anderegg@princeton.edu

andersn@princeton.edu

andrade@princeton.edu

andreap@princeton.edu

andrewtt@princeton.edu

andreww@princeton.edu

andronic@princeton.edu

anewton@princeton.edu

angarone@princeton.edu

angelab@princeton.edu

angelad@princeton.edu

angelaf@princeton.edu

angelams@princeton.edu

angelaq@princeton.edu

angelar@princeton.edu

angelaz@princeton.edu

angelec@princeton.edu

angelh@princeton.edu

angelrs@princeton.edu

angie@princeton.edu

anhpupp@princeton.edu

anickol@princeton.edu

anikolop@princeton.edu

anirudhd@princeton.edu

anna@princeton.edu

annaeto@princeton.edu

annalim@princeton.edu

annetted@princeton.edu

annie.saunders@princeton.edu

anniec@princeton.edu

anoon@princeton.edu

anour@princeton.edu

anovick@princeton.edu

anpingc@princeton.edu

anrpupp@princeton.edu

ansander@princeton.edu

anspupp@princeton.edu

ant6@princeton.edu

antenehs@princeton.edu

anto@princeton.edu

antoinec@princeton.edu

antoinem@princeton.edu

antoniao@princeton.edu

antonioc@princeton.edu

antoniuk@princeton.edu

anunes@princeton.edu

anunno@princeton.edu

anvan@princeton.edu

anwaba@princeton.edu

anyal@princeton.edu

anzalone@princeton.edu

aobaker@princeton.edu

aoberste@princeton.edu

aochang@princeton.edu

aodabas@princeton.edu

aoffit@princeton.edu

aolajide@princeton.edu

aomoses@princeton.edu

aonatema@princeton.edu

aostroff@princeton.edu

aouellet@princeton.edu

aoxiangt@princeton.edu

aoxley@princeton.edu

ap18@princeton.edu

apaasewe@princeton.edu

apalomeq@princeton.edu

apankows@princeton.edu

apapa@princeton.edu

apapp@princeton.edu

aparin@princeton.edu

aparrado@princeton.edu

aparrini@princeton.edu

apastino@princeton.edu

apatten@princeton.edu

apauls@princeton.edu

apayne@princeton.edu

apbarnet@princeton.edu

apd@princeton.edu

apearson@princeton.edu

apellegr@princeton.edu

aperhac@princeton.edu

aperl@princeton.edu

apersat@princeton.edu

apesic@princeton.edu

apetito@princeton.edu

apetkas@princeton.edu

apetsis@princeton.edu

apezzico@princeton.edu

aphidd@princeton.edu

api2@princeton.edu

apimente@princeton.edu

apiotrow@princeton.edu

apirc@princeton.edu

apjpupp@princeton.edu

apl@princeton.edu

apl2@princeton.edu

aplacidi@princeton.edu

aplaks@princeton.edu

apleus@princeton.edu

aplisko@princeton.edu

aploss@princeton.edu

apm2@princeton.edu

apoemer@princeton.edu

aponte@princeton.edu

aportes@princeton.edu

apouschi@princeton.edu

appaul@princeton.edu

appel@cs.princeton.edu

appelget@princeton.edu

appleton@princeton.edu

appling@princeton.edu

appupp@princeton.edu

aprillee@princeton.edu

aprilm@princeton.edu

aprilp@princeton.edu

aprilw@princeton.edu

aprocacc@princeton.edu

apruitt@princeton.edu

apsantos@princeton.edu

apszczol@princeton.edu

apugh@princeton.edu

apval@princeton.edu

apyros@princeton.edu

aqayyum@princeton.edu

aqeelp@princeton.edu

aqu@princeton.edu

aquetell@princeton.edu

aqz2@princeton.edu

ar21@princeton.edu

aracelis@princeton.edu

araghu@princeton.edu

arahlin@princeton.edu

araiffe@princeton.edu

arakhit@princeton.edu

arangan@princeton.edu

aranjan@princeton.edu

aranyaj@princeton.edu

aranzato@princeton.edu

arauch@princeton.edu

aravikum@princeton.edu

arazeto@princeton.edu

arcamone@princeton.edu

archbald@princeton.edu

archen@princeton.edu

arcomano@princeton.edu

arcpupp@princeton.edu

ardans@princeton.edu

aregent@princeton.edu

aretakis@princeton.edu

arfans@princeton.edu

arfarina@princeton.edu

argumbs@princeton.edu

arhowe@princeton.edu

ariaa@princeton.edu

ariadnit@princeton.edu

aricanli@princeton.edu

arich1@princeton.edu

arincon@princeton.edu

arisa@princeton.edu

arjunk@princeton.edu

armitan@princeton.edu

arnavj@princeton.edu

arner@princeton.edu

arnold@princeton.edu

arobinso@princeton.edu

arod@princeton.edu

arodier@princeton.edu

arodnyan@princeton.edu

arodriqu@princeton.edu

aronell@princeton.edu

arora@cs.princeton.edu

arosenb@princeton.edu

arotherm@princeton.edu

arr2@princeton.edu

arr3@princeton.edu

arsalan@princeton.edu

arshe@princeton.edu

arstwo@princeton.edu

artemk@princeton.edu

arthree@princeton.edu

arthuras@princeton.edu

arturf@princeton.edu

arubin@princeton.edu

aruder@princeton.edu

arumpark@princeton.edu

arunnels@princeton.edu

aruship@princeton.edu

arvindn@princeton.edu

arwalter@princeton.edu

arye@princeton.edu

aryeetey@princeton.edu

aryehnc@princeton.edu

as28@princeton.edu

as29@princeton.edu

as31@princeton.edu

as36@princeton.edu

as37@princeton.edu

as40@princeton.edu

as7@princeton.edu

asachee@princeton.edu

asadeghi@princeton.edu

asafarov@princeton.edu

asagan@princeton.edu

asaha@princeton.edu

asamanta@princeton.edu

asambu@princeton.edu

asanand@princeton.edu

asandova@princeton.edu

asapp@princeton.edu

asapping@princeton.edu

asarchi@princeton.edu

asauret@princeton.edu

asavares@princeton.edu

asavaris@princeton.edu

asaxena@princeton.edu

ascardic@princeton.edu

ascheetz@princeton.edu

aschheim@princeton.edu

aschulz@princeton.edu

asday@princeton.edu

asebiomo@princeton.edu

aseegers@princeton.edu

aselloni@princeton.edu

asenju@princeton.edu

asfaw@princeton.edu

asfour@princeton.edu

asg3@princeton.edu

asg4@princeton.edu

asgarza@princeton.edu

asgow@princeton.edu

asgro@princeton.edu

ashadell@princeton.edu

ashafer@princeton.edu

ashahin@princeton.edu

ashantep@princeton.edu

ashanti@princeton.edu

ashaver@princeton.edu

asheff@princeton.edu

ashenhav@princeton.edu

ashephar@princeton.edu

ashibles@princeton.edu

ashkuda@princeton.edu

ashleenk@princeton.edu

ashleycw@princeton.edu

ashleyed@princeton.edu

ashleyl@princeton.edu

ashleylj@princeton.edu

ashleynl@princeton.edu

ashleyp@princeton.edu

ashleyr@princeton.edu

ashrager@princeton.edu

ashwinp@princeton.edu

asibley@princeton.edu

asifg@princeton.edu

asigilli@princeton.edu

asirya@princeton.edu

asjkim@princeton.edu

asked@princeton.edu

askiab@princeton.edu

askline@princeton.edu

asl2@princeton.edu

aslaski@princeton.edu

asliang@princeton.edu

aslihank@princeton.edu

asliski@princeton.edu

asliwins@princeton.edu

aslp@princeton.edu

asm@princeton.edu

asmits@princeton.edu

asmyles@princeton.edu

asnelson@princeton.edu

asodhi@princeton.edu

asodin@princeton.edu

asoest@princeton.edu

asolway@princeton.edu

asommers@princeton.edu

asottil@princeton.edu

asparrin@princeton.edu

aspataru@princeton.edu

aspears@princeton.edu

aspenw@princeton.edu

asr3@princeton.edu

asriniva@princeton.edu

assaini@princeton.edu

asstewar@princeton.edu

astahl@princeton.edu

astariko@princeton.edu

astates@princeton.edu

astepano@princeton.edu

astevens@princeton.edu

astoica@princeton.edu

astout@princeton.edu

asuczews@princeton.edu

asultan@princeton.edu

asw2@princeton.edu

aswoboda@princeton.edu

asylvain@princeton.edu

aszczuka@princeton.edu

aszhou@princeton.edu

at7@princeton.edu

atadych@princeton.edu

atait@princeton.edu

atamasi@princeton.edu

ataneja@princeton.edu

atapupp@princeton.edu

ataranov@princeton.edu

atarr@princeton.edu

atate@princeton.edu

ataturk@princeton.edu

atb@princeton.edu

atcharni@princeton.edu

atchekho@princeton.edu

atel@princeton.edu

ateriba@princeton.edu

aterrett@princeton.edu

athawani@princeton.edu

atherame@princeton.edu

atian@princeton.edu

atibere@princeton.edu

atif@princeton.edu

atkalych@princeton.edu

atkelly@princeton.edu

atkinson@princeton.edu

atn@princeton.edu

atodorov@princeton.edu

atoles@princeton.edu

atollefs@princeton.edu

atompary@princeton.edu

atran@princeton.edu

atrierwe@princeton.edu

atropina@princeton.edu

ats6@princeton.edu

atsue@princeton.edu

atsuron@princeton.edu

atvazque@princeton.edu

atward@princeton.edu

atyryshk@princeton.edu

au2@princeton.edu

audreyb@princeton.edu

audreyl@princeton.edu

audreymj@princeton.edu

aueda@princeton.edu

august@princeton.edu

augustap@princeton.edu

augustin@princeton.edu

aulcej@princeton.edu

ault@princeton.edu

aupperco@princeton.edu

aupshur@princeton.edu

austenm@princeton.edu

austin.bye@princeton.edu

austin@princeton.edu

austinlw@princeton.edu

austinw@princeton.edu

auttamad@princeton.edu

autumnp@princeton.edu

ava.torjani@princeton.edu

avac@princeton.edu

avah@princeton.edu

avalen@princeton.edu

avaneesh.narla@princeton.edu

avanney@princeton.edu

aveekd@princeton.edu

aveillar@princeton.edu

avelkar@princeton.edu

avelozo@princeton.edu

avens@princeton.edu

averys@princeton.edu

avhill@princeton.edu

aviva@princeton.edu

avmarino@princeton.edu

avonhalle@princeton.edu

avora@princeton.edu

avukasin@princeton.edu

aw10@princeton.edu

aw11@princeton.edu

aw14@princeton.edu

aw9@princeton.edu

awalczak@princeton.edu

awalen@princeton.edu

awamsted@princeton.edu

awaryjas@princeton.edu

awbrooks@princeton.edu

awen@princeton.edu

awerth@princeton.edu

awetterm@princeton.edu

awfish@princeton.edu

awfour@princeton.edu

awhite@princeton.edu

awilczek@princeton.edu

awildat@princeton.edu

awildish@princeton.edu

awilkins@princeton.edu

awimmer@princeton.edu

awindawi@princeton.edu

awinter@princeton.edu

awiprud@princeton.edu

awkenney@princeton.edu

awlee@princeton.edu

awohl@princeton.edu

awojak@princeton.edu

aword@princeton.edu

aworsley@princeton.edu

awright@princeton.edu

awsu@princeton.edu

awsun@princeton.edu

axcelson@princeton.edu

axel@princeton.edu

axie@princeton.edu

ay6@princeton.edu

ayac@princeton.edu

ayanc@princeton.edu

ayau@princeton.edu

ayin@princeton.edu

ayjones@princeton.edu

ayk@princeton.edu

aylaa@princeton.edu

aynsleyv@princeton.edu

ayork@princeton.edu

aywong@princeton.edu

ayxu@princeton.edu

azabicki@princeton.edu

azadbood@princeton.edu

azaheri@princeton.edu

azavala@princeton.edu

azeltner@princeton.edu

azhiboed@princeton.edu

azhou@princeton.edu

azmar@princeton.edu

azp@princeton.edu

azwicker@princeton.edu

azxie@princeton.edu

babates@princeton.edu

babbin@princeton.edu

babbylh@princeton.edu

babdi@princeton.edu

babinski@princeton.edu

badessa@princeton.edu

badger@princeton.edu

baenglis@princeton.edu

bafoster@princeton.edu

bajohnso@princeton.edu

bajpayee@princeton.edu

balaji@princeton.edu

balgobin@princeton.edu

balletta@princeton.edu

balramo@princeton.edu

balt@princeton.edu

bandilla@princeton.edu

banfield@princeton.edu

banghart@princeton.edu

bantilan@princeton.edu

baow@princeton.edu

bapark@princeton.edu

baperry@princeton.edu

baptista@princeton.edu

bar@princeton.edu

barajas@princeton.edu

baranski@princeton.edu

barbarac@princeton.edu

barbaram@princeton.edu

barbaraz@princeton.edu

barber@princeton.edu

barberio@princeton.edu

barbieri@princeton.edu

barbiero@princeton.edu

barbour@princeton.edu

bargavi@princeton.edu

barkwell@princeton.edu

barlom@princeton.edu

barobert@princeton.edu

baronian@princeton.edu

barowsky@princeton.edu

barresse@princeton.edu

barriola@princeton.edu

barron@princeton.edu

barryj@princeton.edu

bartels@princeton.edu

barthur@princeton.edu

bartv@princeton.edu

baru@princeton.edu

basaldua@princeton.edu

baschaef@princeton.edu

bashwood@princeton.edu

basuroy@princeton.edu

bataylor@princeton.edu

batnitzk@princeton.edu

bauchner@princeton.edu

baughman@princeton.edu

baumolw@fasecon.econ.nyu.edu

bausmith@princeton.edu

bauster@princeton.edu

bautista@princeton.edu

bax@princeton.edu

bazarsky@princeton.edu

bb2@princeton.edu

bb7@princeton.edu

bb8@princeton.edu

bbadua@princeton.edu

bbassler@princeton.edu

bbender@princeton.edu

bbenedet@princeton.edu

bberling@princeton.edu

bberman@princeton.edu

bbernard@princeton.edu

bbhogal@princeton.edu

bbixler@princeton.edu

bbj@princeton.edu

bbloom@princeton.edu

bboren@princeton.edu

bbpupp@princeton.edu

bbrada@princeton.edu

bbradstr@princeton.edu

bbriones@princeton.edu

bbristol@princeton.edu

bbroadhu@princeton.edu

bbrumfie@princeton.edu

bbscott@princeton.edu

bbw@princeton.edu

bc6@princeton.edu

bcabrez@princeton.edu

bcakir@princeton.edu

bcallaha@princeton.edu

bcampbel@princeton.edu

bcarrow@princeton.edu

bcarvalh@princeton.edu

bcbrown@princeton.edu

bccho@princeton.edu

bcerutti@princeton.edu

bcfour@princeton.edu

bchance@princeton.edu

bchateli@princeton.edu

bcheng@princeton.edu

bcherisl@princeton.edu

bchinery@princeton.edu

bchou@princeton.edu

bchuang@princeton.edu

bchung@princeton.edu

bcitterb@princeton.edu

bckeller@princeton.edu

bclam@princeton.edu

bcliu@princeton.edu

bclyons@princeton.edu

bcole@princeton.edu

bcomella@princeton.edu

bcomo@princeton.edu

bconcepc@princeton.edu

bconlon@princeton.edu

bcormack@princeton.edu

bcpupp@princeton.edu

bculver@princeton.edu

bcwrone@princeton.edu

bdalziel@princeton.edu

bdavis@princeton.edu

bdbell@princeton.edu

bdenzer@princeton.edu

bderuosi@princeton.edu

bdetomma@princeton.edu

bdevlin@princeton.edu

bdiehl@princeton.edu

bdigiova@princeton.edu

bdiner@princeton.edu

bdiorio@princeton.edu

bdjaja@princeton.edu

bdoherty@princeton.edu

bdongre@princeton.edu

bdriscol@princeton.edu

bdsinger@princeton.edu

bdul@princeton.edu

bduncan@princeton.edu

bduthil@princeton.edu

bdyer@princeton.edu

bearnold@princeton.edu

beasop@princeton.edu

beaver@princeton.edu

beavers@princeton.edu

bebong@princeton.edu

becca@princeton.edu

beckley@princeton.edu

beckyg@princeton.edu

bedinger@princeton.edu

bedmonds@princeton.edu

bef@princeton.edu

beg2@princeton.edu

behrmann@princeton.edu

beisner@princeton.edu

beiwang@princeton.edu

bejjanki@princeton.edu

belanger@princeton.edu

belbruno@princeton.edu

belcher@princeton.edu

beley@princeton.edu

belgacem@princeton.edu

belgrave@princeton.edu

belindac@princeton.edu

beliu@princeton.edu

bellan@princeton.edu

belluck@princeton.edu

beltrani@princeton.edu

bemmrich@princeton.edu

ben.gross@princeton.edu

bencbaer@princeton.edu

bender@princeton.edu

benedelman@princeton.edu

benitez@princeton.edu

benitog@princeton.edu

benj@princeton.edu

benjamin.lei@princeton.edu

benjamintso18@princeton.edu

benjh@princeton.edu

benmoshe@princeton.edu

benrose@princeton.edu

benshoof@princeton.edu

benwu@princeton.edu

benzhang@princeton.edu

benziger@princeton.edu

berbecel@princeton.edu

berchick@princeton.edu

bercuson@princeton.edu

bergeson@princeton.edu

bergsten@princeton.edu

berkiten@princeton.edu

bermeo@princeton.edu

bernardo@princeton.edu

bernardp@princeton.edu

bernatp@princeton.edu

bernevig@princeton.edu

berry@princeton.edu

bertal@princeton.edu

bertalan@princeton.edu

bertasi@princeton.edu

bertelli@princeton.edu

berthah@princeton.edu

besposti@princeton.edu

bethleel@princeton.edu

bethp@princeton.edu

bethwang@princeton.edu

betteann@princeton.edu

beveride@princeton.edu

bewing@princeton.edu

beytelma@princeton.edu

bfang@princeton.edu

bfavetta@princeton.edu

bferda@princeton.edu

bfield@princeton.edu

bfifield@princeton.edu

bfitzger@princeton.edu

bfitzwat@princeton.edu

bfp@princeton.edu

bfp2@princeton.edu

bfpaap@princeton.edu

bfridman@princeton.edu

bfruhlin@princeton.edu

bfulgini@princeton.edu

bg6@princeton.edu

bg7@princeton.edu

bga@princeton.edu

bgaines@princeton.edu

bgallo@princeton.edu

bgellman@princeton.edu

bgeren@princeton.edu

bgersh@princeton.edu

bgjura@princeton.edu

bgleason@princeton.edu

bglendon@princeton.edu

bglisic@princeton.edu

bgowin@princeton.edu

bgpupp@princeton.edu

bgs2@princeton.edu

bguabli@princeton.edu

bgulden@princeton.edu

bgunnar@princeton.edu

bgurtler@princeton.edu

bgustafs@princeton.edu

bguzman@princeton.edu

bgy@princeton.edu

bh6@princeton.edu

bhaines@princeton.edu

bhalford@princeton.edu

bharathb@princeton.edu

bharaths@princeton.edu

bhargava@princeton.edu

bharrop@princeton.edu

bhb@princeton.edu

bhe@princeton.edu

bheisler@princeton.edu

bhensley@princeton.edu

bherrera@princeton.edu

bherring@princeton.edu

bhgilber@princeton.edu

bhhummel@princeton.edu

bhilton@princeton.edu

bhlange@princeton.edu

bhmoon@princeton.edu

bhofmann@princeton.edu

bholmes@princeton.edu

bholom@princeton.edu

bholt@princeton.edu

biancad@princeton.edu

bick@princeton.edu

bifoster@princeton.edu

bigjohn@princeton.edu

bigoness@princeton.edu

bihuniak@princeton.edu

bilardi@princeton.edu

bilegieu@princeton.edu

bill@princeton.edu

billington@princeton.edu

billyo@princeton.edu

bingd@princeton.edu

bingqing@princeton.edu

bingram@princeton.edu

binguo@princeton.edu

bino@princeton.edu

binx@princeton.edu

birkhold@princeton.edu

bizcj8co@princeton.edu

bjacobow@princeton.edu

bjacques@princeton.edu

bjarvie@princeton.edu

bjd@princeton.edu

bjedic@princeton.edu

bjenkins@princeton.edu

bjh4@princeton.edu

bjlong@princeton.edu

bjmiller@princeton.edu

bjolson@princeton.edu

bjonsson@princeton.edu

bjs4@princeton.edu

bjsanfor@princeton.edu

bjust@princeton.edu

bjvarga@cs.princeton.edu

bk@princeton.edu

bkadosh@princeton.edu

bkbrewer@princeton.edu

bke@princeton.edu

bkingram@princeton.edu

bkment@princeton.edu

bko@princeton.edu

bkoel@princeton.edu

bkoger@princeton.edu

bkpupp@princeton.edu

bkrenz@princeton.edu

bksmith@princeton.edu

bl@princeton.edu

bl6@princeton.edu

blackey@princeton.edu

blafleur@princeton.edu

blainec@princeton.edu

blairw@princeton.edu

blakee@princeton.edu

blakef@princeton.edu

blalgudi@princeton.edu

blandrum@princeton.edu

blaneyke@princeton.edu

blattler@princeton.edu

blawrenc@princeton.edu

blawson@princeton.edu

blawton@princeton.edu

blax@princeton.edu

bld2@princeton.edu

bleahy@princeton.edu

bleblanc@princeton.edu

blechman@princeton.edu

blei@princeton.edu

bleire@princeton.edu

bleizman@princeton.edu

blewis@princeton.edu

blim@princeton.edu

blin@princeton.edu

blinder@princeton.edu

blleavey@princeton.edu

blmurphy@princeton.edu

blnguyen@princeton.edu

blogan@princeton.edu

blong@princeton.edu

blount@princeton.edu

blovdahl@princeton.edu

blpupp@princeton.edu

blucey@princeton.edu

bludwig@princeton.edu

blz@princeton.edu

bm12@princeton.edu

bm6@princeton.edu

bma@princeton.edu

bmacfarl@princeton.edu

bmachta@princeton.edu

bmacleod@princeton.edu

bmahoney@princeton.edu

bmalkiel@princeton.edu

bmatejek@princeton.edu

bmay@princeton.edu

bmccall@princeton.edu

bmccorma@princeton.edu

bmcdavid@princeton.edu

bmeisenm@princeton.edu

bmelesse@princeton.edu

bmerkel@princeton.edu

bmh2@princeton.edu

bmikeo@princeton.edu

bmilien@princeton.edu

bmj@princeton.edu

bmmiller@princeton.edu

bmobrien@princeton.edu

bmonsen@princeton.edu

bmooring@princeton.edu

bmorgan@princeton.edu

bmorison@princeton.edu

bmreilly@princeton.edu

bmurphy@princeton.edu

bnaar@princeton.edu

bnagel@princeton.edu

bnazari@princeton.edu

bnb@princeton.edu

bneely@princeton.edu

bnehoran@princeton.edu

bnichol@princeton.edu

bnj@princeton.edu

bnl@princeton.edu

bnmcgrat@princeton.edu

bnpupp@princeton.edu

boatman@princeton.edu

bobc@princeton.edu

boberg@princeton.edu

bobh@princeton.edu

bocarsly@princeton.edu

bochaow@princeton.edu

bock@princeton.edu

bodnar@princeton.edu

bodurian@princeton.edu

bogucki@princeton.edu

boguinia@princeton.edu

boguo@princeton.edu

bohara@princeton.edu

bokada@princeton.edu

bombieri@princeton.edu

bomurphy@princeton.edu

bondioli@princeton.edu

bonhomme@princeton.edu

bonin@princeton.edu

bonini@princeton.edu

bopupp@princeton.edu

bordelon@princeton.edu

borislav@princeton.edu

borneman@princeton.edu

bornkamp@princeton.edu

boroughs@princeton.edu

bortolon@princeton.edu

boryanah@princeton.edu

boscott@princeton.edu

bose@princeton.edu

boslin@princeton.edu

botstein@princeton.edu

boudette@princeton.edu

boughn@princeton.edu

boulogne@princeton.edu

boulware@princeton.edu

boutrosa@princeton.edu

boweic@princeton.edu

bowen@princeton.edu

bowenz@princeton.edu

boxiao@princeton.edu

boyajian@princeton.edu

boyangs@princeton.edu

boyuanw@princeton.edu

bozdag@princeton.edu

bozhao@princeton.edu

bozowski@princeton.edu

bpacini@princeton.edu

bpan@princeton.edu

bparks@princeton.edu

bpate@princeton.edu

bpaterno@princeton.edu

bpatters@princeton.edu

bpaul@princeton.edu

bpeard@princeton.edu

bpelner@princeton.edu

bpeltz@princeton.edu

bpenick@princeton.edu

bperlmut@princeton.edu

bperrino@princeton.edu

bpethica@princeton.edu

bpgingri@princeton.edu

bpizzola@princeton.edu

bpklkxny@princeton.edu

bpm2@princeton.edu

bpowell@princeton.edu

bptak@princeton.edu

bpula@princeton.edu

bpurcell@princeton.edu

bpwilson@princeton.edu

bquazzo@princeton.edu

bracz@princeton.edu

bradvany@princeton.edu

brahm@princeton.edu

brambley@princeton.edu

brand@princeton.edu

brandon@princeton.edu

brandony@princeton.edu

brandonz@princeton.edu

branikas@princeton.edu

branker@princeton.edu

brankley@princeton.edu

branu@princeton.edu

brathole@princeton.edu

bratton@princeton.edu

brbenson@princeton.edu

brcarter@princeton.edu

bread@princeton.edu

breed@princeton.edu

breimann@princeton.edu

breinke@princeton.edu

brenda@princeton.edu

brendamb@princeton.edu

brennan@princeton.edu

brereton@princeton.edu

brhodes@princeton.edu

brianeb@princeton.edu

brianhg@princeton.edu

brianpsu@princeton.edu

briant@princeton.edu

brice@princeton.edu

bricebhall@princeton.edu

bricer@princeton.edu

bridges@princeton.edu

bridgetd@princeton.edu

brigitta@princeton.edu

brio@princeton.edu

brionc@princeton.edu

bripupp@princeton.edu

brockett@princeton.edu

brody@princeton.edu

brolnick@princeton.edu

brombert@princeton.edu

bronfeld@princeton.edu

bronheim@princeton.edu

brookeh@princeton.edu

brooks@princeton.edu

brooksgu@princeton.edu

brooksp@princeton.edu

brosado@princeton.edu

brosasco@princeton.edu

brose@princeton.edu

brosenfe@princeton.edu

brosenth@princeton.edu

bross@princeton.edu

browder@math.princeton.edu

browning@princeton.edu

brownm@princeton.edu

broza@princeton.edu

brpupp@princeton.edu

brucegb@princeton.edu

bruces@princeton.edu

brudloff@princeton.edu

brunner@princeton.edu

brush@princeton.edu

brzycki@princeton.edu

bs12@princeton.edu

bs14@princeton.edu

bs15@princeton.edu

bsabass@princeton.edu

bsacks@princeton.edu

bsafdi@princeton.edu

bsanborn@princeton.edu

bsantra@princeton.edu

bsapupp@princeton.edu

bsarfaty@princeton.edu

bsb2@princeton.edu

bscelza@princeton.edu

bschaffa@princeton.edu

bschaffe@princeton.edu

bschoene@princeton.edu

bschupsk@princeton.edu

bschwein@princeton.edu

bsevers@princeton.edu

bsgreen@princeton.edu

bshastri@princeton.edu

bshaw@princeton.edu

bshee@princeton.edu

bshih@princeton.edu

bshori@princeton.edu

bshroyce@princeton.edu

bshughes@princeton.edu

bsilva@princeton.edu

bsixto@princeton.edu

bslavin@princeton.edu

bsmoore@princeton.edu

bsnider@princeton.edu

bso@princeton.edu

bsofen@princeton.edu

bsorkin@princeton.edu

bspar@princeton.edu

bstackho@princeton.edu

bstallwo@princeton.edu

bstango@princeton.edu

bstanley@princeton.edu

bstasins@princeton.edu

bstein@princeton.edu

bsudnick@princeton.edu

bsulman@princeton.edu

bswitzer@princeton.edu

bszwast@princeton.edu

btassell@princeton.edu

btate@princeton.edu

btbyrne@princeton.edu

btchen@princeton.edu

btcohen@princeton.edu

bthapa@princeton.edu

bthomas@princeton.edu

bthompso@princeton.edu

btien@princeton.edu

btobias@princeton.edu

btomlins@princeton.edu

btqwthpf@princeton.edu

btrc@princeton.edu

btso@princeton.edu

btsuang@princeton.edu

budny@princeton.edu

budolfson@princeton.edu

bui@princeton.edu

bulene@princeton.edu

bullock@princeton.edu

bumsook@princeton.edu

buoncore@princeton.edu

buralcan@princeton.edu

burcut@princeton.edu

busch@princeton.edu

buschman@princeton.edu

buser@princeton.edu

bustin@princeton.edu

buz@princeton.edu

bvalenza@princeton.edu

bventimi@princeton.edu

bverreet@princeton.edu

bvickers@princeton.edu

bvpupp@princeton.edu

bvuolo@princeton.edu

bwachtel@princeton.edu

bwalds@princeton.edu

bwatkins@princeton.edu

bway@princeton.edu

bwearl@princeton.edu

bweber@princeton.edu

bwells@princeton.edu

bwhite@princeton.edu

bwiner@princeton.edu

bwitzler@princeton.edu

bwjoyce@princeton.edu

bwk@princeton.edu

bwodnick@princeton.edu

bwolf@princeton.edu

bwoo@princeton.edu

bwthomas@princeton.edu

bwysocka@princeton.edu

byates@princeton.edu

bychang@princeton.edu

byeager@princeton.edu

byoon@princeton.edu

byrne@princeton.edu

byronc@princeton.edu

bzamudio@princeton.edu

bzanghi@princeton.edu

bzawodni@princeton.edu

bzheng@princeton.edu

bzlotnik@princeton.edu

bzoltans@princeton.edu

c6789@princeton.edu

caaurora@princeton.edu

cablakwa@princeton.edu

cabott@princeton.edu

cabral@princeton.edu

cabreros@princeton.edu

cac5@princeton.edu

cac6@princeton.edu

cadava@princeton.edu

caddeau@princeton.edu

cadisant@princeton.edu

cady@princeton.edu

cahearn@princeton.edu

caitlinb@princeton.edu

caitlinw@princeton.edu

cakiti@princeton.edu

cal2@princeton.edu

calbrown@princeton.edu

calder@princeton.edu

calderbk@princeton.edu

calebj@princeton.edu

callton@princeton.edu

calonso@princeton.edu

caltadon@princeton.edu

calvertc@princeton.edu

calvina@princeton.edu

cam13@princeton.edu

camantia@princeton.edu

cameronc@princeton.edu

cameroni@princeton.edu

cameronm@princeton.edu

camn@princeton.edu

campos@princeton.edu

canavera@princeton.edu

candiani@princeton.edu

caneparo@princeton.edu

canojulu@princeton.edu

cantrell@princeton.edu

cap@princeton.edu

capizzi@princeton.edu

cappon@princeton.edu

caprioli@princeton.edu

capunpon@princeton.edu

caran@princeton.edu

cararat@princeton.edu

carazzai@princeton.edu

caresti@princeton.edu

cargon@princeton.edu

carhart@princeton.edu

carisdeo@princeton.edu

carl.segers@princeton.edu

carla@princeton.edu

carlca@princeton.edu

carlesba@princeton.edu

carletti@princeton.edu

carlisle@princeton.edu

carlyg@princeton.edu

carlyj@princeton.edu

carmelia@princeton.edu

carminaa@princeton.edu

carnesen@princeton.edu

caroldh@princeton.edu

carolg@princeton.edu

carolina@princeton.edu

caroljs@princeton.edu

carolp@princeton.edu

carols@princeton.edu

carolyn@princeton.edu

carolynh@princeton.edu

carrazco@princeton.edu

carrieac@princeton.edu

carrieh@princeton.edu

carrier@princeton.edu

carriex@princeton.edu

carringt@princeton.edu

carsonc@princeton.edu

caryliu@princeton.edu

cashaw@princeton.edu

cashmead@princeton.edu

caspupp@princeton.edu

cass@princeton.edu

cassaday@princeton.edu

cassaro@princeton.edu

cassiem@princeton.edu

castano@princeton.edu

cat3@princeton.edu

catalina@princeton.edu

catapang@princeton.edu

catarius@princeton.edu

cathrynf@princeton.edu

cathryng@princeton.edu

cathy.chen@princeton.edu

cathy@princeton.edu

cathym@princeton.edu

cauleus@princeton.edu

caustin@princeton.edu

cavorley@princeton.edu

caw11@princeton.edu

caward@princeton.edu

cayres@princeton.edu

cazoba@princeton.edu

cb@princeton.edu

cb16@princeton.edu

cb2@princeton.edu

cbahri@princeton.edu

cbarale@princeton.edu

cbarmore@princeton.edu

cbarnold@princeton.edu

cbastian@princeton.edu

cbates@princeton.edu

cbaxter@princeton.edu

cbb3@princeton.edu

cbcochra@princeton.edu

cbeach@princeton.edu

cbearns@princeton.edu

cbeck@princeton.edu

cbecnel@princeton.edu

cbeitz@princeton.edu

cbelling@princeton.edu

cbernier@princeton.edu

cbersani@princeton.edu

cbeyerle@princeton.edu

cbgibson@princeton.edu

cbishop@princeton.edu

cbkeller@princeton.edu

cblee@princeton.edu

cboix@princeton.edu

cboone@princeton.edu

cborsack@princeton.edu

cboyce@princeton.edu

cbrangwy@princeton.edu

cbrasz@princeton.edu

cbrinton@princeton.edu

cbrock@princeton.edu

cbroeder@princeton.edu

cbrosows@princeton.edu

cbrower@princeton.edu

cbrownin@princeton.edu

cbrunkho@princeton.edu

cbst@princeton.edu

cbstanto@princeton.edu

cbuff@princeton.edu

cbunzel@princeton.edu

cburkmar@princeton.edu

cbuxo@princeton.edu

cbwells@princeton.edu

cbyers@princeton.edu

cc16@princeton.edu

cc18@princeton.edu

cc21@princeton.edu

cc23@princeton.edu

cc25@princeton.edu

cc26@princeton.edu

cc28@princeton.edu

cc63@princeton.edu

ccallan@princeton.edu

ccameron@princeton.edu

ccampbell@princeton.edu

ccampisa@princeton.edu

ccanal@princeton.edu

ccane@princeton.edu

ccann@princeton.edu

ccap@princeton.edu

ccarano@princeton.edu

ccarman@princeton.edu

ccarney@princeton.edu

ccastens@princeton.edu

ccatalan@princeton.edu

ccb3@princeton.edu

ccerullo@princeton.edu

ccfour@princeton.edu

ccharos@princeton.edu

cchen8@princeton.edu

ccheney@princeton.edu

ccherrey@princeton.edu

cchica@princeton.edu

cchien@princeton.edu

cchuie@princeton.edu

cchung@princeton.edu

cchyba@princeton.edu

cciardie@princeton.edu

ccifelli@princeton.edu

cck@princeton.edu

cclasson@princeton.edu

ccleeton@princeton.edu

cclendin@princeton.edu

ccoffey@princeton.edu

ccomanic@princeton.edu

ccondon@princeton.edu

cconrad@princeton.edu

cconwill@princeton.edu

ccooney@princeton.edu

ccorbeil@princeton.edu

ccornish@princeton.edu

ccpupp@princeton.edu

ccrandell@princeton.edu

ccrifase@princeton.edu

ccritt@princeton.edu

ccrosby@princeton.edu

ccs3@princeton.edu

ccsmith@princeton.edu

ccuff@princeton.edu

cculver@princeton.edu

ccummings@princeton.edu

ccweaver@princeton.edu

cdaron@princeton.edu

cdatwo@princeton.edu

cdavall@princeton.edu

cdc4@princeton.edu

cdecoste@princeton.edu

cderavil@princeton.edu

cdetoro@princeton.edu

cdgum@princeton.edu

cdhess@princeton.edu

cdibilio@princeton.edu

cdickers@princeton.edu

cdimegli@princeton.edu

cdiuk@princeton.edu

cdjones@princeton.edu

cdl2@princeton.edu

cdmartin@princeton.edu

cdochow@princeton.edu

cdoran@princeton.edu

cdreyer@princeton.edu

cdrost@princeton.edu

cdsilva@princeton.edu

cduan@princeton.edu

cdube@princeton.edu

cduprat@princeton.edu

cdussint@princeton.edu

cdwood@princeton.edu

ceakosa@princeton.edu

ceballos@princeton.edu

cebarber@princeton.edu

cebeard@princeton.edu

cebreros@princeton.edu

cebrown@princeton.edu

cecilys@princeton.edu

cedelste@princeton.edu

cefthimi@princeton.edu

cegreene@princeton.edu

ceichler@princeton.edu

cekanem@princeton.edu

cel4@princeton.edu

celenem@princeton.edu

celesten@princeton.edu

celestin@princeton.edu

celford@princeton.edu

celia@princeton.edu

celistan@princeton.edu

celson@princeton.edu

cemerson@princeton.edu

cemilp@princeton.edu

cemyers@princeton.edu

cen@astro.princeton.edu

cengst@princeton.edu

cenmiga@princeton.edu

cer3@princeton.edu

cerenzia@princeton.edu

cergun@princeton.edu

cernst@princeton.edu

ceryan@princeton.edu

cesarp@princeton.edu

ceshaw@princeton.edu

cestrada@princeton.edu

cexken@princeton.edu

cf@math.princeton.edu

cf8@princeton.edu

cfa@princeton.edu

cfairsmi@princeton.edu

cfalk@princeton.edu

cfarrior@princeton.edu

cfaust@princeton.edu

cfazen@princeton.edu

cfelsman@princeton.edu

cfelten@princeton.edu

cfenlon@princeton.edu

cferri@princeton.edu

cfinnega@princeton.edu

cfiocca@princeton.edu

cflitwin@princeton.edu

cflorea@princeton.edu

cflorio@princeton.edu

cflow@princeton.edu

cfmarsh@princeton.edu

cfonseca@princeton.edu

cfrazzet@princeton.edu

cfulton@princeton.edu

cfunk@princeton.edu

cg@princeton.edu

cg11@princeton.edu

cgage@princeton.edu

cgaubert@princeton.edu

cgeddis@princeton.edu

cgentile@princeton.edu

cgerlein@princeton.edu

cgethers@princeton.edu

cgfink@princeton.edu

cgg@princeton.edu

cggross@princeton.edu

cgiglio@princeton.edu

cgking@princeton.edu

cgmachl@princeton.edu

cgmiller@princeton.edu

cgoken@princeton.edu

cgordon@princeton.edu

cgorzeln@princeton.edu

cgrama@princeton.edu

cgranby@princeton.edu

cgreenho@princeton.edu

cgriffit@princeton.edu

cgrogan@princeton.edu

cgross@princeton.edu

cgtully@princeton.edu

cgudasz@princeton.edu

cgui@princeton.edu

cgullick@princeton.edu

cgupta@princeton.edu

cgursky@princeton.edu

ch16@princeton.edu

ch5@princeton.edu

chacker@princeton.edu

chacko@princeton.edu

chadha@princeton.edu

chafey@princeton.edu

chagans@princeton.edu

chaikin@princeton.edu

chailey@princeton.edu

chaisson@princeton.edu

chamberl@princeton.edu

champlin@princeton.edu

chance.fletcher@princeton.edu

chancem@princeton.edu

chandras@princeton.edu

chaneyl@princeton.edu

changgoo@princeton.edu

changguo@princeton.edu

changlee@princeton.edu

changlel@princeton.edu

channon@princeton.edu

chansen@princeton.edu

chantalb@princeton.edu

chanykim@princeton.edu

chaol@princeton.edu

chaoliu@princeton.edu

chaplin@princeton.edu

chappidi@princeton.edu

charania@princeton.edu

chari@princeton.edu

charig@princeton.edu

charlayne.beavers@princeton.edu

charlesh@princeton.edu

charlesr@princeton.edu

charlotte.e.collins@princeton.edu

charmian@princeton.edu

chartoff@princeton.edu

charwood@princeton.edu

chassang@princeton.edu

chatarin@princeton.edu

chatsamp@princeton.edu

chause@princeton.edu

chawins@princeton.edu

chay@princeton.edu

chazelle@cs.princeton.edu

chc2@princeton.edu

chctwo@princeton.edu

chebbi@princeton.edu

cheek@princeton.edu

chefbrad@princeton.edu

cheffred@princeton.edu

chefgary@princeton.edu

chefjery@princeton.edu

chefmann@princeton.edu

chefrob@princeton.edu

chefsal@princeton.edu

chelciet@princeton.edu

cheliu@princeton.edu

chelseai@princeton.edu

chelseaj@princeton.edu

chenchua@princeton.edu

chengsun@princeton.edu

chensley@princeton.edu

chenx@princeton.edu

chenyi@princeton.edu

cherbert@princeton.edu

cherubin@princeton.edu

cheryl@princeton.edu

chex.yu@princeton.edu

chialol@princeton.edu

chiamaka@princeton.edu

chianese@princeton.edu

chiang@princeton.edu

chiangm@princeton.edu

chiaoti@princeton.edu

chiawang@princeton.edu

chiaying@princeton.edu

chichen@princeton.edu

chienc@princeton.edu

chienlu@princeton.edu

chimiak@princeton.edu

chinglee@princeton.edu

chingyao@princeton.edu

chingyuc@princeton.edu

chiounl@princeton.edu

chivetta@princeton.edu

chk4@princeton.edu

chliu@princeton.edu

chng@princeton.edu

choney@princeton.edu

chonggu@princeton.edu

choongc@princeton.edu

choppock@princeton.edu

choran@princeton.edu

chosang@princeton.edu

chou@princeton.edu

choueiri@princeton.edu

choung@princeton.edu

chris@princeton.edu

chrisarm@princeton.edu

chrish@princeton.edu

chrislee@princeton.edu

chrislia@princeton.edu

chrismcc@princeton.edu

chrisw@princeton.edu

chssaine@princeton.edu

chuancun@princeton.edu

chuellst@princeton.edu

chuhan@princeton.edu

chungh@princeton.edu

chunhuih@princeton.edu

chussey@artswebusa.org

chutekan@princeton.edu

chuw@princeton.edu

chyao@princeton.edu

chyland@princeton.edu

cid@princeton.edu

ciepley@princeton.edu

ciharris@princeton.edu

cindy@princeton.edu

cindyd@princeton.edu

cindyl@princeton.edu

cindyliu@princeton.edu

cinmaste@princeton.edu

cip2@princeton.edu

cireilly@princeton.edu

cissyc@princeton.edu

cithomas@princeton.edu

cj8@princeton.edu

cjaffrel@princeton.edu

cjager@princeton.edu

cjagoe@princeton.edu

cjamison@princeton.edu

cjany@princeton.edu

cjavier@princeton.edu

cjbradfo@princeton.edu

cjd2@princeton.edu

cjeeva@princeton.edu

cjeong@princeton.edu

cjf2@princeton.edu

cjfong@princeton.edu

cjgray@princeton.edu

cjh2@princeton.edu

cjha@princeton.edu

cjhenry@princeton.edu

cjhsu@princeton.edu

cjl3@princeton.edu

cjm5@princeton.edu

cjoe@princeton.edu

cjohnson@princeton.edu

cjonay@princeton.edu

cjotter@princeton.edu

cjperez@princeton.edu

cjpeters@princeton.edu

cjs4@princeton.edu

cjs5@princeton.edu

cjt@princeton.edu

cjury@princeton.edu

cjw4@princeton.edu

cjw5@princeton.edu

cjwebb@princeton.edu

cjwhite@princeton.edu

cjyu@princeton.edu

ck@princeton.edu

ck7@princeton.edu

ckandell@princeton.edu

ckanno@princeton.edu

ckanoff@princeton.edu

ckaup@princeton.edu

ckeil@princeton.edu

ckeith@princeton.edu

ckelley@princeton.edu

ckeltz@princeton.edu

ckenny@cs.princeton.edu

ckerwin@princeton.edu

ckessel@princeton.edu

ckf@princeton.edu

ckgay@princeton.edu

ckidd@princeton.edu

ckimmey@princeton.edu

ckircher@princeton.edu

cklaw@princeton.edu

cklumb@princeton.edu

ckmcdona@princeton.edu

ckohut@princeton.edu

ckolb@princeton.edu

ckollmer@princeton.edu

ckomer@princeton.edu

ckopec@princeton.edu

ckorsvik@princeton.edu

ckoscins@princeton.edu

ckphilli@princeton.edu

ckranenb@princeton.edu

ckrank@princeton.edu

ckt@princeton.edu

ckthree@princeton.edu

ckuenne62@princeton.edu

ckung@princeton.edu

ckurpiew@princeton.edu

ckyauk@princeton.edu

cl12@princeton.edu

cl15@princeton.edu

cl19@princeton.edu

cl3@princeton.edu

cl4@princeton.edu

cl9@princeton.edu

clabaugh@princeton.edu

clag@princeton.edu

clago@princeton.edu

claing@princeton.edu

claireec@princeton.edu

clairej@princeton.edu

clairep@princeton.edu

clairerk@princeton.edu

clairh@princeton.edu

clarar@princeton.edu

claras@princeton.edu

claraw@princeton.edu

claretta@princeton.edu

clarkg@princeton.edu

clasky@princeton.edu

clatini@princeton.edu

claudiab@princeton.edu

claudinc@princeton.edu

clausen@princeton.edu

clawson@princeton.edu

claytonb@princeton.edu

clbarlow@princeton.edu

clc3@princeton.edu

clc4@princeton.edu

clc5@princeton.edu

clchen@princeton.edu

cld2@princeton.edu

cldavis@princeton.edu

clem@princeton.edu

clemaire@princeton.edu

clemar@princeton.edu

clementl@princeton.edu

clementw@princeton.edu

cleochou@princeton.edu

clevans@princeton.edu

clevy@princeton.edu

clewis@princeton.edu

clfreema@princeton.edu

cliffb@princeton.edu

cliftonp@princeton.edu

clillja@princeton.edu

climbach@princeton.edu

cliodhna@princeton.edu

clk@princeton.edu

clk2@princeton.edu

clkinney@princeton.edu

clmcmull@princeton.edu

clmuller@princeton.edu

clmurphy@princeton.edu

cloht@princeton.edu

clongo@princeton.edu

clotson@princeton.edu

clove@princeton.edu

clporter@princeton.edu

clrobbin@princeton.edu

clsp@princeton.edu

clu@princeton.edu

clugston@princeton.edu

clulli@princeton.edu

clwood@princeton.edu

clxu@princeton.edu

clzhou@princeton.edu

cm18@princeton.edu

cm19@princeton.edu

cmaher@princeton.edu

cmallet@princeton.edu

cmantz@princeton.edu

cmara@princeton.edu

cmarsh@princeton.edu

cmarti@princeton.edu

cmarx@princeton.edu

cmaskell@princeton.edu

cmayer@princeton.edu

cmb4@princeton.edu

cmbarry@princeton.edu

cmccord@princeton.edu

cmccrack@princeton.edu

cmcfarla@princeton.edu

cmcgrory@princeton.edu

cmcgugan@princeton.edu

cmchow@princeton.edu

cmchugh@princeton.edu

cmcilwai@princeton.edu

cmclaren@princeton.edu

cmcls@princeton.edu

cmcoyle@princeton.edu

cmcrae@princeton.edu

cmedici@princeton.edu

cmenkes@princeton.edu

cmetcalf@princeton.edu

cmetto@princeton.edu

cmetz@princeton.edu

cmfowler@princeton.edu

cmgonzal@princeton.edu

cmguhl@princeton.edu

cmhill@princeton.edu

cmhughes@princeton.edu

cmichels@princeton.edu

cmikulas@princeton.edu

cminervi@princeton.edu

cmj3@princeton.edu

cmjoe@princeton.edu

cmk3@princeton.edu

cmkraml@princeton.edu

cmlittle@princeton.edu

cmmegwa@princeton.edu

cmmiller@princeton.edu

cmmn@princeton.edu

cmmoore@princeton.edu

cmnichol@princeton.edu

cmolin@princeton.edu

cmolina@princeton.edu

cmontfer@princeton.edu

cmoretti@princeton.edu

cmorris@princeton.edu

cmorton@princeton.edu

cmose@princeton.edu

cmoser@princeton.edu

cmoss@princeton.edu

cmowbray@princeton.edu

cmpage@princeton.edu

cmpope@princeton.edu

cmq@princeton.edu

cmsanche@princeton.edu

cmsthree@princeton.edu

cmw3@princeton.edu

cmwalter@princeton.edu

cmwelsh@princeton.edu

cmytelka@princeton.edu

cnadell@princeton.edu

cnalexan@princeton.edu

cnanfra@princeton.edu

cnappi@princeton.edu

cnawrat@princeton.edu

cnegash@princeton.edu

cneikirk@princeton.edu

cnelson@princeton.edu

cnh2@princeton.edu

cnichola@princeton.edu

cnickers@princeton.edu

cniles@princeton.edu

cnine@princeton.edu

cnorback@princeton.edu

cnsong@princeton.edu

cnteng@princeton.edu

cnuckols@princeton.edu

cnutter@princeton.edu

co4@princeton.edu

coberto@princeton.edu

cobrien@princeton.edu

codner@princeton.edu

cody@princeton.edu

codyo@princeton.edu

codyp@princeton.edu

codyw@princeton.edu

coev@princeton.edu

coffey@princeton.edu

cofield@princeton.edu

cognetta@princeton.edu

cokekeag@princeton.edu

colbyc@princeton.edu

colbym@princeton.edu

coleary@princeton.edu

colemank@princeton.edu

coles@princeton.edu

colettej@princeton.edu

colgan@princeton.edu

colinw@princeton.edu

collcutt@princeton.edu

colleenk@princeton.edu

colletti@princeton.edu

collins@princeton.edu

collura@princeton.edu

colomina@princeton.edu

colotti@princeton.edu

coltons@princeton.edu

comer@princeton.edu

conlon@princeton.edu

connault@princeton.edu

connieb@princeton.edu

connorjs@princeton.edu

connorm@princeton.edu

connormm@princeton.edu

connorp@princeton.edu

conoline@princeton.edu

conorc@princeton.edu

conorf@princeton.edu

conrad@princeton.edu

conradm@princeton.edu

const@princeton.edu

conway@princeton.edu

coppong@princeton.edu

corantes@princeton.edu

corazong@princeton.edu

corban@princeton.edu

corcione@princeton.edu

coreyc@princeton.edu

corillac@princeton.edu

corinnek@princeton.edu

corngold@princeton.edu

corriek@princeton.edu

cos2@princeton.edu

costello@princeton.edu

coswald@princeton.edu

cotiel@princeton.edu

courtneycameron@princeton.edu

cozias@princeton.edu

cp@princeton.edu

cp8@princeton.edu

cpae@princeton.edu

cpalacio@princeton.edu

cpalm@princeton.edu

cpalombo@princeton.edu

cpapadim@princeton.edu

cpappas@princeton.edu

cpblume@princeton.edu

cpchou@princeton.edu

cperales@princeton.edu

cperrucc@princeton.edu

cpetrovi@princeton.edu

cph@princeton.edu

cphinney@princeton.edu

cpidgeon@princeton.edu

cpietsch@princeton.edu

cpoli@princeton.edu

cppupp@princeton.edu

cpreed@princeton.edu

cprier@princeton.edu

cpss@princeton.edu

cqian@princeton.edu

cr11@princeton.edu

cr16@princeton.edu

cra@princeton.edu

crabner@princeton.edu

cradley@princeton.edu

crafford@princeton.edu

craigbh@princeton.edu

craigens@princeton.edu

craighl@princeton.edu

craigjs@princeton.edu

craigl@princeton.edu

craigm@princeton.edu

craigpj@princeton.edu

craigrp@princeton.edu

cramer@princeton.edu

creager@princeton.edu

creitz@princeton.edu

crgorman@princeton.edu

crichmnd@princeton.edu

criley@princeton.edu

crippin@princeton.edu

cristins@princeton.edu

critelli@princeton.edu

crivelli@princeton.edu

crj2@princeton.edu

crjohnso@princeton.edu

crkelley@princeton.edu

crmarsh@princeton.edu

crmoore@princeton.edu

cro@princeton.edu

croames@princeton.edu

crobinso@princeton.edu

crojas@princeton.edu

crosland@princeton.edu

crosley@princeton.edu

crosser@princeton.edu

crouse@princeton.edu

crovner@princeton.edu

croy@princeton.edu

crpupp@princeton.edu

crrichar@princeton.edu

crs3@princeton.edu

crsmith@princeton.edu

crthomas@princeton.edu

crtucker@princeton.edu

cruffis@princeton.edu

crystalh@princeton.edu

crystalw@princeton.edu

crystaly@princeton.edu

cs2@princeton.edu

cs21@princeton.edu

cs3@princeton.edu

csada@princeton.edu

csagnier@princeton.edu

csahner@princeton.edu

csain@princeton.edu

csall@princeton.edu

csallade@princeton.edu

csamuels@princeton.edu

csands@princeton.edu

csanz@princeton.edu

csavadge@princeton.edu

csaville@princeton.edu

csbu@princeton.edu

csburke@princeton.edu

csc3@princeton.edu

cscarval@princeton.edu

cschlesi@princeton.edu

cschlom@princeton.edu

cschwart@princeton.edu

cscimeca@princeton.edu

cscott1@princeton.edu

cseal@princeton.edu

csealfon@princeton.edu

cseguin@princeton.edu

csellman@princeton.edu

cshang@princeton.edu

cshawcro@princeton.edu

csherlog@princeton.edu

cshi@princeton.edu

cshin@princeton.edu

cshort@princeton.edu

cshumate@princeton.edu

csiettos@princeton.edu

csipupp@princeton.edu

cskang@princeton.edu

csked@princeton.edu

cskinner@princeton.edu

csliu@princeton.edu

csm3@princeton.edu

csn@princeton.edu

csnider@princeton.edu

csong@princeton.edu

csosa@princeton.edu

csotelo@princeton.edu

cspark@princeton.edu

cspero@princeton.edu

cspupp@princeton.edu

csreilly@princeton.edu

cssbrad@princeton.edu

csschwar@princeton.edu

csstone@princeton.edu

cstaggs@princeton.edu

cstan@princeton.edu

cstapfer@princeton.edu

cstedman@princeton.edu

csteinha@princeton.edu

csterner@princeton.edu

cstevers@princeton.edu

cstibitz@princeton.edu

cstires@princeton.edu

cstry@princeton.edu

csu@princeton.edu

csuch@princeton.edu

csuter@princeton.edu

cswain@princeton.edu

cswilson@princeton.edu

cswoboda@princeton.edu

ct17@princeton.edu

ct9@princeton.edu

ctan@princeton.edu

ctasker@princeton.edu

ctenenba@princeton.edu

ctfortin@princeton.edu

ctheriau@princeton.edu

cthiel@princeton.edu

cthompso@princeton.edu

cthorkel@princeton.edu

ctmurphy@princeton.edu

ctobin@princeton.edu

ctoddr@princeton.edu

ctorney@princeton.edu

ctulloch@princeton.edu

ctuten@princeton.edu

ctwiname@princeton.edu

ctwomey@princeton.edu

ctyler@princeton.edu

cuff@princeton.edu

cuiz@princeton.edu

curcic@princeton.edu

currie@princeton.edu

curry@princeton.edu

curt@princeton.edu

curtishs@princeton.edu

curtisj@princeton.edu

curtislb@princeton.edu

curtvk@princeton.edu

cutrell@princeton.edu

cvansant@princeton.edu

cvaughn@princeton.edu

cvelasco@princeton.edu

cvenkatr@princeton.edu

cverile@princeton.edu

cveto@princeton.edu

cvettier@princeton.edu

cvitale@princeton.edu

cvolz@princeton.edu

cvpupp@princeton.edu

cvwang@princeton.edu

cw20@princeton.edu

cw23@princeton.edu

cwaldron@princeton.edu

cwampole@princeton.edu

cwarkala@princeton.edu

cwatsky@princeton.edu

cwax@princeton.edu

cweber@princeton.edu

cwelsch@princeton.edu

cwerth@princeton.edu

cwest@princeton.edu

cwgash@princeton.edu

cwhitehe@princeton.edu

cwhunter@princeton.edu

cwidman@princeton.edu

cwillett@princeton.edu

cwilliam@princeton.edu

cwillis@princeton.edu

cwkessel@princeton.edu

cwmurphy@princeton.edu

cwojtkow@princeton.edu

cwperron@princeton.edu

cwrowley@princeton.edu

cwthree@princeton.edu

cwu16@princeton.edu

cwulfman@princeton.edu

cwulns@princeton.edu

cwyang@princeton.edu

cxduan@princeton.edu

cxie@princeton.edu

cycruz@princeton.edu

cydney@princeton.edu

cyee@princeton.edu

cyliu@princeton.edu

cyork@princeton.edu

cypark@princeton.edu

cythree@princeton.edu

cyuk@princeton.edu

cz2@princeton.edu

cz3@princeton.edu

czanca@princeton.edu

czandone@princeton.edu

czarakas@princeton.edu

czeng@princeton.edu

czimowsk@princeton.edu

czrada@princeton.edu

czyan@princeton.edu

daashley@princeton.edu

dabell@princeton.edu

dabreu@princeton.edu

dabrown@princeton.edu

dabtwo@princeton.edu

dad@princeton.edu

dadaly@princeton.edu

dade@princeton.edu

dadrados@princeton.edu

dafermos@princeton.edu

dahyuno@princeton.edu

dainan@princeton.edu

daisyl@princeton.edu

dakshs@princeton.edu

daksoy@princeton.edu

dalexand@princeton.edu

dalfonso@princeton.edu

daliao@princeton.edu

dalizio@princeton.edu

dally@princeton.edu

dan@princeton.edu

danaglei@princeton.edu

danailov@princeton.edu

danas@princeton.edu

dancasey@princeton.edu

danderso@princeton.edu

danelle@princeton.edu

danielts@princeton.edu

danielw@princeton.edu

dannyf@princeton.edu

dannyrf@princeton.edu

dansley@princeton.edu

danson@princeton.edu

danted@princeton.edu

dantonuc@princeton.edu

daphne.ireland@princeton.edu

daphnee@princeton.edu

daphney@princeton.edu

darcy@princeton.edu

darekj@princeton.edu

darius@princeton.edu

dariusa@princeton.edu

darmouni@princeton.edu

darnton@princeton.edu

daronov@princeton.edu

darrow@princeton.edu

darshana@princeton.edu

darwin@princeton.edu

das6@princeton.edu

daskin@princeton.edu

datang@princeton.edu

datc@princeton.edu

datwater@princeton.edu

daud@princeton.edu

dauphiny@princeton.edu

davaa@princeton.edu

dave.herrington@princeton.edu

david.stickland@cern.ch

davidfl@princeton.edu

davidlam@princeton.edu

davidlee@princeton.edu

davidnd@princeton.edu

davidw@princeton.edu

davina@princeton.edu

dawncm@princeton.edu

dawnm@princeton.edu

dawnmp@princeton.edu

dawnwang@princeton.edu

dawtwo@princeton.edu

daye@princeton.edu

daynaj@princeton.edu

db1@princeton.edu

dbabic@princeton.edu

dbackes@princeton.edu

dbaena@princeton.edu

dbaer@princeton.edu

dbaldwin@princeton.edu

dbalitz@princeton.edu

dball@princeton.edu

dbalsamo@princeton.edu

dbanacis@princeton.edu

dbansal@princeton.edu

dbarolia@princeton.edu

dbashore@princeton.edu

dbattagl@princeton.edu

dbborens@princeton.edu

dbcarter@princeton.edu

dbeavens@princeton.edu

dbellos@princeton.edu

dbeneven@princeton.edu

dbeohmer@princeton.edu

dberlo@princeton.edu

dbhattac@princeton.edu

dbland@princeton.edu

dblong@princeton.edu

dbohr@princeton.edu

dbondar@princeton.edu

dborsuk@princeton.edu

dbowen@princeton.edu

dboyle@princeton.edu

dbozym@princeton.edu

dbpalmer@princeton.edu

dbulkilv@princeton.edu

dbuzatu@princeton.edu

dc27@princeton.edu

dc33@princeton.edu

dc34@princeton.edu

dc4@princeton.edu

dc6@princeton.edu

dcannadi@princeton.edu

dcapupp@princeton.edu

dcarlino@princeton.edu

dcassel@princeton.edu

dcching@princeton.edu

dcekirge@princeton.edu

dcfive@princeton.edu

dcfoster@princeton.edu

dchin@princeton.edu

dchoo@princeton.edu

dchouren@princeton.edu

dchpupp@princeton.edu

dcifelli@princeton.edu

dcioppa@princeton.edu

dclay@princeton.edu

dcmurphy@princeton.edu

dcnami@princeton.edu

dcody@princeton.edu

dcoley@princeton.edu

dconte@princeton.edu

dcook@princeton.edu

dcordero@princeton.edu

dcordoba@princeton.edu

dcorreia@princeton.edu

dcox@princeton.edu

dcramire@princeton.edu

dcskemer@princeton.edu

dcx@princeton.edu

dcylinde@princeton.edu

dd4@princeton.edu

ddabbs@princeton.edu

ddagci@princeton.edu

ddarabi@princeton.edu

ddavies@princeton.edu

ddavoudi@princeton.edu

ddebened@princeton.edu

ddebonis@princeton.edu

ddemszky@princeton.edu

ddiehl@princeton.edu

ddnguyen@princeton.edu

ddobkin@princeton.edu

ddohan@princeton.edu

ddorsett@princeton.edu

ddreyer@princeton.edu

ddreyfus@princeton.edu

ddunham@princeton.edu

ddurst@princeton.edu

ddyrda@princeton.edu

de4@princeton.edu

deanal@princeton.edu

deast@princeton.edu

deaton@princeton.edu

debayan@princeton.edu

debbield@princeton.edu

debbiet@princeton.edu

debetten@princeton.edu

deborah@princeton.edu

deborahk@princeton.edu

debrap@princeton.edu

debraski@princeton.edu

deffeyes@princeton.edu

defran@princeton.edu

degiulio@princeton.edu

degolian@princeton.edu

dehaas@princeton.edu

deionk@princeton.edu

deirdreg@princeton.edu

deirdrer@princeton.edu

delaney@princeton.edu

delepine@princeton.edu

dellings@princeton.edu

dely@princeton.edu

demarest@princeton.edu

dembroff@princeton.edu

demeyer@princeton.edu

dempupp@princeton.edu

den@princeton.edu

denise@princeton.edu

denised@princeton.edu

dennisds@princeton.edu

dennisg@princeton.edu

denniss@princeton.edu

denunzio@princeton.edu

dereka@princeton.edu

derekb@princeton.edu

derekp@princeton.edu

dericc@princeton.edu

derrickd@princeton.edu

dertiano@princeton.edu

desandro@princeton.edu

deshogan@princeton.edu

despagne@princeton.edu

desu@princeton.edu

deuce@princeton.edu

devakig@princeton.edu

devanshg@princeton.edu

devergne@princeton.edu

devika@princeton.edu

devonj@princeton.edu

devonmh@princeton.edu

dew@princeton.edu

dewoskin@princeton.edu

dexume@princeton.edu

dfabrici@princeton.edu

dfahmy@princeton.edu

dfang@princeton.edu

dfara@princeton.edu

dfarago@princeton.edu

dfarias@princeton.edu

dfassin@princeton.edu

dfeehan@princeton.edu

dfeeney@princeton.edu

dfiedler@princeton.edu

dflesch@princeton.edu

dfmartin@princeton.edu

dfoldesi@princeton.edu

dfore@princeton.edu

dforeman@princeton.edu

dfridovi@princeton.edu

dfscott@princeton.edu

dfuss@princeton.edu

dg3@princeton.edu

dg4@princeton.edu

dgabai@princeton.edu

dgalbi@princeton.edu

dgarber@princeton.edu

dgarcia@princeton.edu

dgates@princeton.edu

dgeyer@princeton.edu

dghersi@princeton.edu

dghoffma@princeton.edu

dgibson@princeton.edu

dgildow@princeton.edu

dgkim@princeton.edu

dglover@princeton.edu

dgoetz@princeton.edu

dgolac@princeton.edu

dgpupp@princeton.edu

dgrissom@princeton.edu

dgroce@princeton.edu

dgrtwo@princeton.edu

dgruver@princeton.edu

dgulla@princeton.edu

dgupta@princeton.edu

dgupupp@princeton.edu

dguyett@princeton.edu

dgwilson@princeton.edu

dh11@princeton.edu

dhager@princeton.edu

dhart@princeton.edu

dharvey@princeton.edu

dhaw@princeton.edu

dhazen@princeton.edu

dhchin@princeton.edu

dheller@princeton.edu

dhenreck@princeton.edu

dhensley@princeton.edu

dheyer@princeton.edu

dheyman@princeton.edu

dhfour@princeton.edu

dhighland@princeton.edu

dhnguyen@princeton.edu

dhock@princeton.edu

dhocker@princeton.edu

dhoffman@princeton.edu

dholland@princeton.edu

dhopkins@princeton.edu

dhorner@princeton.edu

dhosie@princeton.edu

dhouck@princeton.edu

dhuber@princeton.edu

dhungana@princeton.edu

dhyi@princeton.edu

diallo@princeton.edu

dianacm@princeton.edu

dianali@princeton.edu

dianam@princeton.edu

dianeg@princeton.edu

dianehu@princeton.edu

dianemic@princeton.edu

dianna@princeton.edu

diannaf@princeton.edu

dianne@princeton.edu

diannek@princeton.edu

dibekwe@princeton.edu

dicintil@princeton.edu

didonato@princeton.edu

diegoa@princeton.edu

diegos@princeton.edu

dietrick@princeton.edu

difelice@princeton.edu

dih@princeton.edu

diller@princeton.edu

dillone@princeton.edu

diloreto@princeton.edu

dimaggio@princeton.edu

dinac@princeton.edu

dinarag@princeton.edu

dincerti@princeton.edu

dineen@princeton.edu

dino@princeton.edu

dipietro@princeton.edu

dipippo@princeton.edu

dir@princeton.edu

dismukes@princeton.edu

distasio@princeton.edu

dito@princeton.edu

dittrich@princeton.edu

diubaldi@princeton.edu

divyak@princeton.edu

divyas@princeton.edu

divyat@princeton.edu

dixitak@princeton.edu

dj3@princeton.edu

djacobow@princeton.edu

djantzen@princeton.edu

djbeck@princeton.edu

djc4@princeton.edu

djeffay@princeton.edu

djeon@princeton.edu

djgonzal@princeton.edu

djharris@princeton.edu

djimenez@princeton.edu

djjarvis@princeton.edu

djjohnso@princeton.edu

djkeddie@princeton.edu

djlong@princeton.edu

djr@princeton.edu

djuarez@princeton.edu

dkaki@princeton.edu

dkaple@princeton.edu

dkaretni@princeton.edu

dkblanks@princeton.edu

dkellett@princeton.edu

dkenealy@princeton.edu

dkennedy@princeton.edu

dkhodges@princeton.edu

dkinsey@princeton.edu

dklam@princeton.edu

dknorr@princeton.edu

dkoenigs@princeton.edu

dkoffman@princeton.edu

dkoltuny@princeton.edu

dkong@princeton.edu

dkoon@princeton.edu

dkrisilo@princeton.edu

dkrotov@princeton.edu

dkumar@princeton.edu

dkurtzer@princeton.edu

dl2pupp@princeton.edu

dl3@princeton.edu

dlabrie@princeton.edu

dlapins@princeton.edu

dlavalle@princeton.edu

dlawler@princeton.edu

dlawrenc@princeton.edu

dlboyce@princeton.edu

dlclark@princeton.edu

dldezarn@princeton.edu

dleach@princeton.edu

dleheny@princeton.edu

dleiderm@princeton.edu

dlenger@princeton.edu

dlenning@princeton.edu

dleong@princeton.edu

dlezan@princeton.edu

dlhargad@princeton.edu

dlidow@princeton.edu

dliebent@princeton.edu

dliese@princeton.edu

dlight@princeton.edu

dlinke@princeton.edu

dlivi@princeton.edu

dlm@princeton.edu

dlnelson@princeton.edu

dlockhar@princeton.edu

dloesser@princeton.edu

dloevner@princeton.edu

dlondon@princeton.edu

dlopes@princeton.edu

dlowe@princeton.edu

dltubbs@princeton.edu

dlustig@princeton.edu

dlzhu@princeton.edu

dm19@princeton.edu

dm25@princeton.edu

dmackey@princeton.edu

dmacmill@princeton.edu

dmacy@princeton.edu

dmagier@princeton.edu

dmaher@princeton.edu

dmajor@princeton.edu

dmakino@princeton.edu

dmalghan@princeton.edu

dmansfield@princeton.edu

dmarconi@princeton.edu

dmartind@princeton.edu

dmassey@princeton.edu

dmbecker@princeton.edu

dmcbride@princeton.edu

dmccall@princeton.edu

dmccarth@princeton.edu

dmcclure@princeton.edu

dmcgady@princeton.edu

dmcgowan@princeton.edu

dmckay@princeton.edu

dmcnesb@princeton.edu

dmcr@princeton.edu

dmcreyno@princeton.edu

dmdb@princeton.edu

dmeade@princeton.edu

dmedvigy@princeton.edu

dmejias@princeton.edu

dmichta@princeton.edu

dmills@princeton.edu

dmistree@princeton.edu

dmitch@princeton.edu

dmitri@princeton.edu

dmitriyg@princeton.edu

dmitryp@princeton.edu

dmlarson@princeton.edu

dmliao@princeton.edu

dmoak@princeton.edu

dmolk@princeton.edu

dmontana@princeton.edu

dmueller@princeton.edu

dmusial@princeton.edu

dmyeong@princeton.edu

dn15@princeton.edu

dnabosse@princeton.edu

dnagy@princeton.edu

dnapier@princeton.edu

dnarayan@princeton.edu

dneeff@princeton.edu

dnelson@princeton.edu

dnh@princeton.edu

dnieves@princeton.edu

dnord@princeton.edu

dns@astro.princeton.edu

do@princeton.edu

doakes@princeton.edu

doakley@princeton.edu

dobber@princeton.edu

dobromir@princeton.edu

dochen@princeton.edu

docteau@princeton.edu

doemland@princeton.edu

doepking@princeton.edu

dofori@princeton.edu

dogden@princeton.edu

dolinski@princeton.edu

dolivan@princeton.edu

doliver@princeton.edu

dolores@princeton.edu

dolsen@princeton.edu

domenica@princeton.edu

domni@princeton.edu

donaldd@princeton.edu

donaldem@princeton.edu

donaldh@princeton.edu

donaldr@princeton.edu

doncat@princeton.edu

donggyun@princeton.edu

donghwa@princeton.edu

dongw@princeton.edu

dongwono@princeton.edu

dongxian@princeton.edu

donnacha@princeton.edu

donnamw@princeton.edu

donofrio@princeton.edu

dons@princeton.edu

donsimon@princeton.edu

dooleys@princeton.edu

doppenhe@princeton.edu

dorac@princeton.edu

dorantes@princeton.edu

doreens@princeton.edu

dorianj@princeton.edu

dorianw@princeton.edu

dorothy@princeton.edu

dorothyt@princeton.edu

dottie@princeton.edu

dou@princeton.edu

doug@cs.princeton.edu

doug@princeton.edu

doughert@princeton.edu

downey@princeton.edu

dp12@princeton.edu

dpacheco@princeton.edu

dpal@princeton.edu

dparks@princeton.edu

dpaulk@princeton.edu

dpavlis@princeton.edu

dpdesai@princeton.edu

dpease@princeton.edu

dpedulla@princeton.edu

dpennoni@princeton.edu

dperler@princeton.edu

dpg@princeton.edu

dphelan@princeton.edu

dpicott@princeton.edu

dpopper@princeton.edu

dpramos@princeton.edu

dpw@princeton.edu

dpyla@princeton.edu

drago@princeton.edu

draine@astro.princeton.edu

drakeman@princeton.edu

dravid@princeton.edu

dreffner@princeton.edu

dreisman@princeton.edu

drepupp@princeton.edu

dreynold@princeton.edu

driedl@princeton.edu

drigoll@princeton.edu

driskell@princeton.edu

dritzman@princeton.edu

drivera@princeton.edu

drizzo@princeton.edu

drodgers@princeton.edu

drohira@princeton.edu

drolan@princeton.edu

drolston@princeton.edu

drosso@princeton.edu

drperry@princeton.edu

drwatson@princeton.edu

ds2@princeton.edu

ds29@princeton.edu

ds3@princeton.edu

ds4@princeton.edu

ds5@princeton.edu

ds7@princeton.edu

dsa8@princeton.edu

dsacke@princeton.edu

dsago@princeton.edu

dsaint@princeton.edu

dsallade@princeton.edu

dsanner@princeton.edu

dsantam@princeton.edu

dsantoro@princeton.edu

dscerbo@princeton.edu

dschen@princeton.edu

dschlein@princeton.edu

dschlich@princeton.edu

dschlper@princeton.edu

dschmitt@princeton.edu

dschulte@princeton.edu

dschunk@princeton.edu

dschwab@princeton.edu

dscotton@princeton.edu

dsethi@princeton.edu

dsferra@princeton.edu

dshahmd@princeton.edu

dsharp@princeton.edu

dsharris@princeton.edu

dsherman@princeton.edu

dshum@princeton.edu

dsigurda@princeton.edu

dsivco@princeton.edu

dslegall@princeton.edu

dslimmer@princeton.edu

dslobodi@princeton.edu

dslotten@princeton.edu

dsmith@princeton.edu

dsnead@princeton.edu

dsnook@princeton.edu

dsoler@princeton.edu

dsolodka@princeton.edu

dsouza@princeton.edu

dspatafo@princeton.edu

dspoth@princeton.edu

dssteven@princeton.edu

dstassi@princeton.edu

dstearns@princeton.edu

dsteinbe@princeton.edu

dstern@princeton.edu

dstirk@princeton.edu

dstorton@princeton.edu

dstotler@princeton.edu

dstrauss@princeton.edu

dstrouse@princeton.edu

dswantek@princeton.edu

dsyamane@princeton.edu

dt3@princeton.edu

dtantivi@princeton.edu

dtbs@princeton.edu

dtchen@princeton.edu

dtf@princeton.edu

dthinojo@princeton.edu

dtierney@princeton.edu

dtindall@princeton.edu

dtingley@princeton.edu

dtitus@princeton.edu

dtlake@princeton.edu

dtle@princeton.edu

dtomlin@princeton.edu

dtrivedi@princeton.edu

dtrueman@princeton.edu

dtsement@princeton.edu

dtv@princeton.edu

dtwalker@princeton.edu

dtye@princeton.edu

duanyi@princeton.edu

duct@princeton.edu

dudek@princeton.edu

duffy@princeton.edu

dufner@princeton.edu

duliba@princeton.edu

dumaine@princeton.edu

duncanh@princeton.edu

dunderwo@princeton.edu

dunkley@princeton.edu

dunnd@princeton.edu

dupre@princeton.edu

durang@princeton.edu

durkee@princeton.edu

durrani@princeton.edu

dusa@princeton.edu

duyu@princeton.edu

dvaliev@princeton.edu

dvallejo@princeton.edu

dvarnell@princeton.edu

dvega@princeton.edu

dvereen@princeton.edu

dvicuna@princeton.edu

dvives@princeton.edu

dvon@princeton.edu

dvoorhee@princeton.edu

dvsmith@princeton.edu

dvuong@princeton.edu

dwebster@princeton.edu

dweil@princeton.edu

dweinryb@princeton.edu

dwhowell@princeton.edu

dwilcove@princeton.edu

dwill@princeton.edu

dwillifo@princeton.edu

dwjohnso@princeton.edu

dwkatz@princeton.edu

dwm@princeton.edu

dwmcdona@princeton.edu

dwmiller@princeton.edu

dworden@princeton.edu

dworsky@princeton.edu

dworthy@princeton.edu

dwrenn@princeton.edu

dwright@princeton.edu

dwtank@princeton.edu

dwthomps@princeton.edu

dwweil@princeton.edu

dx@princeton.edu

dxie@princeton.edu

dxin@princeton.edu

dxue@princeton.edu

dxzheng@princeton.edu

dyadav@princeton.edu

dyashar@princeton.edu

dyeung@princeton.edu

dylanb@princeton.edu

dylang@princeton.edu

dylanja@princeton.edu

dyxu@princeton.edu

dz@princeton.edu

dzapecza@princeton.edu

dzechner@princeton.edu

dzhang@princeton.edu

dzhernok@princeton.edu

dzhu@princeton.edu

dzhuo@princeton.edu

dziegler@princeton.edu

dzwang@princeton.edu

eab3@princeton.edu

eabbasza@princeton.edu

eabbe@princeton.edu

eabt@princeton.edu

eac@princeton.edu

ead@princeton.edu

eadler@princeton.edu

eadom@princeton.edu

eagle@princeton.edu

eagreenb@princeton.edu

eahenry@princeton.edu

eahmed@princeton.edu

eak2@princeton.edu

ealdred@princeton.edu

ealer@princeton.edu

eanagbo@princeton.edu

eapupp@princeton.edu

ear2@princeton.edu

earonson@princeton.edu

easchh@princeton.edu

easdavis@princeton.edu

easwjp@princeton.edu

eatiq@princeton.edu

eatu@princeton.edu

eavery@princeton.edu

eawang@princeton.edu

eayers@princeton.edu

eb11@princeton.edu

ebaikoff@princeton.edu

ebaker@princeton.edu

ebanes@princeton.edu

ebarnett@princeton.edu

ebarth@princeton.edu

ebarton@princeton.edu

ebbou@princeton.edu

ebc2@princeton.edu

ebelova@princeton.edu

ebeninte@princeton.edu

ebergin@princeton.edu

ebhuang@princeton.edu

ebird@princeton.edu

ebj@astro.princeton.edu

ebmiller@princeton.edu

ebobrick@princeton.edu

ebogan@princeton.edu

eboix@princeton.edu

ebolten@princeton.edu

ebonner@princeton.edu

ebourbou@princeton.edu

ebouzeid@princeton.edu

ebprice@princeton.edu

ebpupp@princeton.edu

ebrahimi@princeton.edu

ebray@princeton.edu

ebreza@princeton.edu

ebrindle@princeton.edu

ebroch@princeton.edu

ebrooks@princeton.edu

ebrower@princeton.edu

ebroyles@princeton.edu

ebrugge@princeton.edu

ebrumley@princeton.edu

ebruns@princeton.edu

ebuck@princeton.edu

ebuehler@princeton.edu

ebulling@princeton.edu

ebunlomo@princeton.edu

eburr@princeton.edu

ebush@princeton.edu

ebutterf@princeton.edu

ebyrd@princeton.edu

ec4@princeton.edu

ec7@princeton.edu

ec8@princeton.edu

ecampa@princeton.edu

ecancilla@princeton.edu

ecapetti@princeton.edu

ecasey@princeton.edu

ecava@princeton.edu

ecchen@princeton.edu

ecdavis@princeton.edu

ecermano@princeton.edu

echances@princeton.edu

echeruiy@princeton.edu

echhor@princeton.edu

echiarel@princeton.edu

echin@princeton.edu

echo@princeton.edu

echow@princeton.edu

echuang@princeton.edu

ecinlar@princeton.edu

ecjones@princeton.edu

eckerlee@princeton.edu

ecking@princeton.edu

ecleary@princeton.edu

ecm@princeton.edu

ecmorales@princeton.edu

ecolagiu@princeton.edu

ecole@princeton.edu

ecollins@princeton.edu

ecooke@princeton.edu

ecorden@princeton.edu

ecox@princeton.edu

ecpatten@princeton.edu

ecrowe@princeton.edu

ecsnyder@princeton.edu

ecurran@princeton.edu

ecvo@princeton.edu

ecwood@princeton.edu

ecxu@princeton.edu

eczajkow@princeton.edu

ed5@princeton.edu

ed6@princeton.edu

edalton@princeton.edu

edames@princeton.edu

edanzige@princeton.edu

edavies@princeton.edu

edchase@princeton.edu

edcmeyer@princeton.edu

eddyjean@princeton.edu

edejesus@princeton.edu

edelgado@princeton.edu

edelmann@princeton.edu

edelsten@princeton.edu

edeluca@princeton.edu

edepaz@princeton.edu

edepupp@princeton.edu

edganley@princeton.edu

edgarc@princeton.edu

edgarp@princeton.edu

edgarw@princeton.edu

edgary@princeton.edu

edghill@princeton.edu

edibened@princeton.edu

edieleke@princeton.edu

eding@princeton.edu

edipippo@princeton.edu

edixon@princeton.edu

edlarsen@princeton.edu

edmaine@princeton.edu

edmondk@princeton.edu

edo@princeton.edu

edodeles@princeton.edu

edolan@princeton.edu

edonahue@princeton.edu

edpupp@princeton.edu

edraim@princeton.edu

edrogers@princeton.edu

edwardaw@princeton.edu

edwardcr@princeton.edu

edwarde@princeton.edu

edwardl@princeton.edu

edwardmb@princeton.edu

edwardmn@princeton.edu

edwardpz@princeton.edu

edwardrn@princeton.edu

edwardwl@princeton.edu

edwardy@princeton.edu

edwardyw@princeton.edu

edwin@princeton.edu

edzhou@princeton.edu

eeaston@princeton.edu

eebong@princeton.edu

eeglash@princeton.edu

eem2@princeton.edu

een@princeton.edu

eengel@princeton.edu

eengelha@princeton.edu

eenourat@princeton.edu

eenrique@princeton.edu

eepanay@princeton.edu

eephrem@princeton.edu

eerdenee@princeton.edu

eerickso@princeton.edu

eettinghausen@princeton.edu

eewhitak@princeton.edu

efeibush@princeton.edu

efiguero@princeton.edu

efjenkin@princeton.edu

eflax@princeton.edu

efluehr@princeton.edu

efoos@princeton.edu

efowler@princeton.edu

efredd@princeton.edu

efredric@princeton.edu

efreelan@princeton.edu

efrobert@princeton.edu

efull@princeton.edu

efuller@princeton.edu

efw@princeton.edu

efwillia@princeton.edu

efwood@princeton.edu

eg6@princeton.edu

egarcia@princeton.edu

egarlow@princeton.edu

egatto@princeton.edu

egatzogi@princeton.edu

egbell@princeton.edu

ege@princeton.edu

egedrich@princeton.edu

egelb@princeton.edu

egentry@princeton.edu

egibbs@princeton.edu

egilson@princeton.edu

egiovine@princeton.edu

egleeson@princeton.edu

eglennon@princeton.edu

egooden@princeton.edu

egoshey@princeton.edu

egossman@princeton.edu

egrabbi@princeton.edu

egrace@princeton.edu

egraser@princeton.edu

egreen@princeton.edu

egreenst@princeton.edu

egriffis@princeton.edu

egrimes@princeton.edu

egroves@princeton.edu

eh2@princeton.edu

eh7@princeton.edu

ehaddad@princeton.edu

ehamblin@princeton.edu

eharden@princeton.edu

eharman@princeton.edu

ehaselsw@princeton.edu

ehazan@princeton.edu

ehchoi@princeton.edu

ehepler@princeton.edu

ehernand@princeton.edu

ehgilson@princeton.edu

ehirsch@princeton.edu

ehogan@princeton.edu

eholden@princeton.edu

eholovac@princeton.edu

ehong@princeton.edu

ehorlick@princeton.edu

ehorn@princeton.edu

ehornsby@princeton.edu

ehpupp@princeton.edu

ehr@princeton.edu

ehstern@princeton.edu

ehtu@princeton.edu

ehubbard@princeton.edu

ehulme@princeton.edu

eichbaum@princeton.edu

eichen@princeton.edu

eija@princeton.edu

eileenk@princeton.edu

einat@princeton.edu

eireilly@princeton.edu

eisenach@princeton.edu

eisgruber@princeton.edu

ejacoby@princeton.edu

ejb3@princeton.edu

ejburt@princeton.edu

ejdepuy@princeton.edu

ejeng@princeton.edu

ejeongb@princeton.edu

ejfoley@princeton.edu

eji@princeton.edu

ejj6@princeton.edu

ejking@princeton.edu

ejlee@princeton.edu

ejlu@princeton.edu

ejmartin@princeton.edu

ejohn@princeton.edu

ejoo@princeton.edu

ejs@princeton.edu

ejweiss@princeton.edu

ejzhang@princeton.edu

ekaeser@princeton.edu

ekahler@princeton.edu

ekamen@princeton.edu

ekaris@princeton.edu

ekarns@princeton.edu

ekast@princeton.edu

ekearns@princeton.edu

ekennedy@princeton.edu

ekenny@princeton.edu

ekent@princeton.edu

ekiesele@princeton.edu

ekirgios@princeton.edu

ekite@princeton.edu

ekmcbrid@princeton.edu

eknott@princeton.edu

eknudson@princeton.edu

ekolemen@princeton.edu

ekolmes@princeton.edu

ekonick@princeton.edu

ekontor@princeton.edu

ekotsior@princeton.edu

ekoyuncu@princeton.edu

ekpowell@princeton.edu

ekraeck@princeton.edu

ekratzer@princeton.edu

ekubu@princeton.edu

ekuhn@princeton.edu

ekyoon@princeton.edu

el5@princeton.edu

el7@princeton.edu

elaffey@princeton.edu

elaines@princeton.edu

elamarca@princeton.edu

elanders@princeton.edu

elapenta@princeton.edu

elarson@princeton.edu

elatham@princeton.edu

elba@princeton.edu

elberson@princeton.edu

elbrecht@princeton.edu

elburke@princeton.edu

elcole@princeton.edu

elena@princeton.edu

elenach@princeton.edu

elever@princeton.edu

elhochbe@princeton.edu

elian@princeton.edu

eliese@princeton.edu

elijah.schiltz@princeton.edu

elima@princeton.edu

elinton@princeton.edu

eliotj@princeton.edu

elisew@princeton.edu

elitosta@princeton.edu

elitz@princeton.edu

eliza13@princeton.edu

elizabethspencer@princeton.edu

elizberg@princeton.edu

elizp@princeton.edu

eljones@princeton.edu

eljung@princeton.edu

elkent@princeton.edu

ell@princeton.edu

ellac@princeton.edu

ellenr@princeton.edu

elliotc@princeton.edu

elliots@princeton.edu

elman@princeton.edu

eloizard@princeton.edu

elonl@princeton.edu

eloredo@princeton.edu

elpupp@princeton.edu

elsaw@princeton.edu

elspeth@princeton.edu

elturner@princeton.edu

eluchak@princeton.edu

eludvig@princeton.edu

elundstr@princeton.edu

elviras@princeton.edu

em18@princeton.edu

em19@princeton.edu

em2@princeton.edu

em4@princeton.edu

ema@princeton.edu

emachuga@princeton.edu

emad@princeton.edu

emaier@princeton.edu

emansfie@princeton.edu

emanso@princeton.edu

emanuela@princeton.edu

emanuelc@princeton.edu

emaritz@princeton.edu

emaselli@princeton.edu

emastro@princeton.edu

emathis@princeton.edu

ematsumo@princeton.edu

emaxey@princeton.edu

embird@princeton.edu

embrown@princeton.edu

emccoy@princeton.edu

emcgee@princeton.edu

emckenzi@princeton.edu

emcnamee@princeton.edu

emcpartl@princeton.edu

emcveigh@princeton.edu

eme2@princeton.edu

ememet@princeton.edu

emerino@princeton.edu

emeyers@princeton.edu

emhyde@princeton.edu

emilam@princeton.edu

emilceas@princeton.edu

emilied@princeton.edu

emiliemk@princeton.edu

emilyas@princeton.edu

emilyc@princeton.edu

emilych@princeton.edu

emilycl@princeton.edu

emilycr@princeton.edu

emilyhsu@princeton.edu

emilyl@princeton.edu

emilymk@princeton.edu

emilyo@princeton.edu

emilysn@princeton.edu

emilyt@princeton.edu

emilyvm@princeton.edu

emilyz@princeton.edu

emintz@princeton.edu

emm2@princeton.edu

emmag@princeton.edu

emmaj@princeton.edu

emmamm@princeton.edu

emmao@princeton.edu

emmasw@princeton.edu

emopupp@princeton.edu

emora@princeton.edu

emorton@princeton.edu

emott@princeton.edu

empondo@princeton.edu

emreynol@princeton.edu

ems3@princeton.edu

emschnei@princeton.edu

emsthree@princeton.edu

emthomps@princeton.edu

emurfit@princeton.edu

enagel@princeton.edu

enassar@princeton.edu

end@princeton.edu

enegron@princeton.edu

eneida@princeton.edu

eng@princeton.edu

engelste@princeton.edu

enicolas@princeton.edu

enjik@princeton.edu

enmills@princeton.edu

enoh@princeton.edu

enonez@princeton.edu

enriqueg@princeton.edu

enugent@princeton.edu

enzevaee@princeton.edu

eoboh@princeton.edu

eobrien@princeton.edu

eokelly@princeton.edu

eonaran@princeton.edu

eop@princeton.edu

eopupp@princeton.edu

eoshima@princeton.edu

eosime@princeton.edu

eostrike@princeton.edu

eovalle@princeton.edu

eowens@princeton.edu

eoyu@princeton.edu

ep8@princeton.edu

epackin@princeton.edu

epagels@princeton.edu

epaine@princeton.edu

epaluck@princeton.edu

epapouts@princeton.edu

eparham@princeton.edu

epas@princeton.edu

epatten@princeton.edu

epaul@princeton.edu

epearl@princeton.edu

epeng@princeton.edu

eperkins@princeton.edu

eperry@princeton.edu

epetcu@princeton.edu

epierce@princeton.edu

epierson@princeton.edu

eplink@princeton.edu

epowers@princeton.edu

eprapas@princeton.edu

epritt@princeton.edu

eprodan@princeton.edu

epronin@princeton.edu

eqhansen@princeton.edu

equansah@princeton.edu

eramirez@princeton.edu

erb2@princeton.edu

erchang@princeton.edu

ereardon@princeton.edu

ereeves@princeton.edu

erentzou@princeton.edu

erez@princeton.edu

ereznik@princeton.edu

ergilson@princeton.edu

erhee@princeton.edu

ericchen@princeton.edu

erichard@princeton.edu

erickson@princeton.edu

ericpaul@princeton.edu

erik@princeton.edu

erikad@princeton.edu

erikaw@princeton.edu

erikf@princeton.edu

erikmm@princeton.edu

erikr@princeton.edu

eripley@princeton.edu

eripupp@princeton.edu

eriscoe@princeton.edu

erise@princeton.edu

ermiller@princeton.edu

ermolaev@princeton.edu

ernesths@princeton.edu

ernieg@princeton.edu

ero2@princeton.edu

erobbins@princeton.edu

erodas@princeton.edu

erolfe@princeton.edu

eromanzi@princeton.edu

erosen@princeton.edu

uconn-tubarc

Tuesday, August 5, 2014

Princeton University – Plundering of Science I

Cornell – I do NOT understand my PATENTS XXX

This is the tip of the iceberg as of what lies bellow, clearly points out distorted conceptions and beliefs on human culture WHEN LAWS OF MAN IGNORE LAWS OF NATURE.

You are a fool---

If you can’t understand legal or technical writing, you have no business blogging about it

“Wicking” is a term of art---fluid will travel in any direction via the fibers—regardless of gravity

-------------------

"Wick/wicking is in the patent classification system but not on HYDROLOGY textbooks."

Sir Isaac Newton defined the Law of Universal Gravitation in 1687. He was inspired to formulate his theory of gravitation by watching the fall of an apple from a tree.

UC SANTA BARBARA I, II, III

No comments:

Post a Comment